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Developmental Pediatric Dentistry Lab
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The lab studies how children's teeth form, starting from the molecular level.
AboutAbout the lab
Aiming for the healthy development of children's mouths.
The Developmental Pediatric Dentistry Lab conducts broad research on children, aiming for the healthy development of the oral cavity in childhood.
Teeth are formed through the complex interaction of many molecules.
The lab investigates the relationships among these molecules, analyzing the mechanisms of tooth formation and working on technologies for tooth regeneration.
It also applies the image analysis techniques developed in its cell biology research to the evaluation of clinical images and new dental materials.
Key terms
- Ameloblasts
- Cells that form enamel, the material covering the surface of teeth.
- Ectoderm-derived cells
- Cells that originate from the ectoderm, one of the cell layers formed in early development. They give rise to tissues such as skin and nerves.
- Calcification
- The process in which minerals such as calcium are deposited, turning tissue into hard tissue.
- Dental caries
- Commonly known as cavities.
ResearchResearch themes
The Developmental Pediatric Dentistry Lab conducts broad research on children, aiming for the healthy development of the oral cavity in childhood. Dental disorders include odontoma, supernumerary teeth, congenitally missing teeth, enamel hypoplasia, and dentin hypoplasia, and teeth are formed through the complex interaction of many molecules.
*Illustrative imageMechanisms of tooth formation and regeneration
The lab untangles the relationships among molecules, analyzing the mechanisms of tooth formation and working on technologies for tooth regeneration. It has also emerged that ameloblasts can be induced to differentiate into other ectoderm-derived cells, and that inducing calcification may suppress tumors.
*Illustrative imageEvaluating clinical images and dental materials through image analysis
Using image analysis techniques developed in cell biology research, the lab evaluates clinical images and new dental materials. In the clinic, it works not only on caries prevention but also on assessing children's growth and on diagnostic imaging.
MembersFaculty
- ProfessorKan Saito
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Dentist in Mexico attending a child” Miguel Angel Omaña Rojas / CC BY 4.0 (cropped)
- Mechanisms of tooth formation and regeneration: “Tooth Smile” Pathologist without beard / CC BY 4.0 (cropped)
- Evaluating clinical images and dental materials through image analysis: “HIPODONCIA DENTAL” Ramirotomasi / CC BY-SA 4.0 (cropped)
- Related lab (Endodontology and Periodontology Lab): “A dental chair in a dentist clinic in North Carolina, United States” Harrison Keely / CC BY 4.0 (cropped)
- Related lab (Oral Pathology Lab): “Hooke Microscope-03000276-FIG-4” 作者不詳 / Public domain (cropped)
- Related lab (Oral and Maxillofacial Tissue Development Lab): “Slide under a microscope” Waughd / CC BY-SA 4.0 (cropped)
- Related lab (Oral and Maxillofacial Oncologic Surgery Lab): “Serum-separation tube” Spiritia / CC BY-SA 4.0 (cropped)
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