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Dermatology Lab
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A dermatology lab that investigates the mechanisms and treatment of skin diseases.
AboutAbout the lab
Contributing to community healthcare and sharing research results worldwide
The Dermatology Lab studies how diseases such as systemic sclerosis and skin cancer arise, and develops new treatments for them.
The lab also provides clinical care as the Department of Dermatology of Tohoku University Hospital, and the professor, associate professor, and lecturer each have their own research themes.
The lab's philosophy is "to train medical professionals and members of society who are truly useful to people," and it aims to contribute to community healthcare and share its research results with the world.
Founded in 1907, the lab has a long history and has produced many research results on skin diseases.
Key terms
- Systemic sclerosis
- A systemic autoimmune disease characterized by damage to blood vessels in the skin and internal organs, and by fibrosis. It is designated an intractable disease by the Japanese government
- Transcription factor
- A protein that regulates whether genes are turned on or off, and how strongly they are active
- Tumor-associated macrophage
- An immunosuppressive immune cell found within tumors. Monocytes in the blood enter the tumor and acquire this function
NewsLab news
A paper by a dermatology physician was published in Eur J Dermatol
A paper by a dermatology physician was published in Eur J Dermatol
A paper by a dermatology physician was published in J Dermatol
A paper by a dermatology physician was published in J Dermatol
A paper by a dermatology physician was published in J Dermatol
ResearchResearch themes
In the Dermatology Lab, the professor, associate professor, and lecturer each have their own research themes, and investigate the mechanisms of diseases such as systemic sclerosis and skin cancer. The lab aims to turn findings from basic research into new treatments.
*Illustrative imageMechanisms of systemic sclerosis
The lab found that reduced expression of the transcription factor FLI1 is one important disease factor in systemic sclerosis. Using genetically modified mice and other models, it studies the transcriptional network involved in the disease and new treatments that target it.
*Illustrative imageNew treatments for melanoma
The lab is developing a new immunotherapy for melanoma that inhibits a molecule called PAI-1. Based on basic research, it conducted an investigator-initiated clinical trial and showed that the therapy can overcome drug resistance in melanoma that no longer responds to anti-PD-1 antibodies.
*Illustrative imageTumor-associated macrophages in skin cancer
The lab focuses on tumor-associated macrophages, which are widely distributed within skin cancer tumors, and studies their role in extramammary Paget's disease, cutaneous T-cell lymphoma, and other cancers. It aims to develop treatments that target them and work across different types of cancer.
*Illustrative imageSkin cancer progression and inflammatory responses
Using the B16F10 mouse model, the lab examines the possibility that ultraviolet light changes the immune environment surrounding a tumor and promotes the progression of skin cancer. It also studies the relationship between weight-bearing stress on the sole of the foot and melanoma progression, and hopes to contribute to preventing the onset and progression of skin cancer.
MembersFaculty
The members of the Dermatology Lab include a Professor, Associate Professor, Lecturer, Assistant Professors and assistants, clinical staff physicians, reduced-hours staff physicians, research fellows, part-time lecturers, and graduate students. Full-time faculty of the Tohoku University Healthspan Research Center also join the lab.As of 2026
- ProfessorYoshihide Asano
- Associate ProfessorTaku Fujimura
- Associate ProfessorTakehiro Takahashi
- LecturerToshiya Takahashi
- Hospital LecturerYumi Kanbayashi
- Assistant ProfessorRyoko Omori
- Assistant ProfessorYusuke Muto
- Assistant ProfessorMayuko Amagai
- Assistant ProfessorYuichiro Segawa
- Assistant (Joshu)Erika Tamabuchi
- Assistant (Joshu)Yurie Segawa
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Dermatoscope1” Frank33 / CC BY-SA 3.0 (cropped)
- Mechanisms of systemic sclerosis: “Transcription factor Creb PDB 1dh3” Emw / CC BY-SA 3.0 (cropped)
- New treatments for melanoma: “Antibody IgG1 surface” Tokenzero / CC BY-SA 4.0 (cropped)
- Tumor-associated macrophages in skin cancer: “Autophagy in macrophage” Kam23lesh / CC BY-SA 4.0 (cropped)
- Skin cancer progression and inflammatory responses: “Cell culture incubator” real name: Nadina Wiórkiewicz pl.wiki: Nadine90 commons: Nadine90 / CC BY-SA 3.0 (cropped)
- Related lab (Hematology Lab): “Myeloid leukemia” Makysm / CC0 (cropped)
- Related lab (Clinical Pharmaceutical Sciences Lab): “Agilent LC-MS” Nick Birse / CC BY-SA 4.0 (cropped)
- Related lab (Neurosurgery Lab): “Operating-room 1” 연세건우병원 / CC BY 4.0 (cropped)
- Related lab (Gynecology Lab): “Air Force's first robotic surgery training course established at Keesler 161021-F-BD983-031” Kemberly Groue / Public domain (cropped)
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