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Regional Oral Health Science Lab (Tohoku Medical Megabank Organization)
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A lab that explores the links between the oral environment and diseases throughout the body.
AboutAbout the lab
Understanding systemic diseases through the oral environment
The Regional Oral Health Science Lab studies the relationship between oral diseases and systemic diseases.
Periodontal disease is deeply involved in the onset and exacerbation of diabetes, preterm birth, respiratory diseases, and cardiovascular and cerebrovascular disorders.
Using multi-omics information, including human genome, metabolome, and metagenome data collected in the large-scale cohort studies of the Tohoku Medical Megabank Organization, together with lifestyle, health, and medical information, the lab analyzes the associations between the oral environment and various diseases.
By analyzing diseases from multiple perspectives to clarify their pathology, the lab aims to improve the quality not only of dental care but of medical care as a whole.
Key terms
- Cohort study
- A study that follows the same group of people over a long period to examine the relationship between lifestyle or health status and disease.
- Multi-omics
- Combining and handling several types of comprehensive data, such as the genome, metabolites, and the genetic information of microorganisms.
- Oral microbiota
- The community of many kinds of bacteria living in the mouth.
ResearchResearch themes
It has become clear that oral diseases are associated with various systemic diseases, centering on lifestyle-related diseases. To clarify how the oral environment and diseases affect each other, the lab analyzes the associations between the two using data from large-scale cohort studies.
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MembersFaculty
- ProfessorRitsuko Shimizu
- LecturerToru Tamahara
- Assistant ProfessorMaki Goto
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Set of dental tools and instruments on a table in a clinic during a procedure” Shixart1985 / CC BY 2.0 (cropped)
- Analysis of associations between the oral environment and systemic diseases: “Illumina Genome Analyzer II System” Jon Callas from San Jose, USA / CC BY 2.0 (cropped)
- Related lab (Pediatric Development Lab (Tohoku Medical Megabank Organization)): “Séquençage du génome d'une microalgue au laboratoire GENALG (Ifremer )” Stephane Lesbats (IFREMER, Pôle Images, Centre Bretagne - ZI de la Pointe du Diable - CS Plouzané, France) / CC BY 4.0 (cropped)
- Related lab (Biomarker Discovery Lab (Tohoku Medical Megabank Organization)): “Blood test samples” Fumikas Sagisavas / CC0 (cropped)
- Related lab (Image Statistics Lab (Tohoku Medical Megabank Organization)): “MRI Scanner” Lizadeborah03 / CC BY-SA 4.0 (cropped)
- Related lab (Genome Medical Science Informatics Lab (Advanced Research Center for Innovations in Next-Generation Medicine)): “DNBSEQ-G400(2)” RPSkokie / CC BY-SA 4.0 (cropped)
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