LAB LOGA page on LabLog, a review site (not the lab's official page)
Microbiology Lab
Machine-translated · View original
A lab that investigates systemic diseases through the relationship between oral microorganisms and immunity.
AboutAbout the lab
Exploring systemic diseases through oral microorganisms
The Microbiology Lab studies microorganisms in the mouth and the body's immune system.
In addition to its long-running research on Mycoplasma and innate immunity, the lab has in recent years been investigating how oral microorganisms affect systemic diseases such as cancer and Alzheimer's disease.
The lab is deepening its research on how the bacteria that cause periodontal disease act on the inflammasome, and on their role within tumors.
The lab was established in 1969 as the Department of Oral Bacteriology and took its current name in 2024.
Key terms
- Innate immunity
- Immunity that quickly detects and eliminates microorganisms that enter the body, using mechanisms the body has had since birth
- Inflammasome
- A protein complex inside cells that senses abnormalities and controls the production of substances that cause inflammation (such as IL-1β)
- Gut microbiota
- The community of many bacteria living in the intestine. It has been found to be linked to the condition of the whole body
NewsLab news
A paper from the lab was accepted by JOB
A paper on research conducted in the lab was accepted by Int J Paediatr Dent
A paper by Prof. Hasebe et al. was published in International Journal of Paediatric Dentistry
A paper by Lecturer Takebe et al. was published in International journal of biological macromolecules
A paper by Prof. Hasebe et al. was published in Hokkaido J Dent Sci
ResearchResearch themes
The lab mainly studies the effects of oral microorganisms on the gut microbiota, the relationship between inflammasomes and inflammatory diseases, and the regulation of gene function using fragments of microbial genomes. It focuses on the interactions between the many bacteria that live in the human body and human cells.
*Illustrative imageHow Oral Bacteria Affect Gut Bacteria
Humans constantly take in oral microorganisms by swallowing them. The lab therefore studies how oral microorganisms, especially Candida albicans, affect the gut microbiota.
*Illustrative imageInflammasomes and Inflammation
The inflammasome is an intracellular sensor that controls the production of the inflammatory cytokines IL-1β and IL-18. The lab has been clarifying the mechanisms by which oral bacteria activate it, and is analyzing those mechanisms in more detail using synthetic lipopeptides derived from Mycoplasma.
*Illustrative imageRegulating Gene Expression with Microbial Gene Fragments
The lab is studying a method for tuning protein levels continuously, by inserting fragments of microbial genomic DNA into the 5' untranslated region of mRNA as sequences that alter its secondary structure.
MembersFaculty
The members of the Microbiology Lab consist of faculty, invited faculty, specialist researchers, and graduate students (including graduate students affiliated with other labs).As of 2026
- ProfessorAkira Hasebe
- LecturerKatsuki Takebe
- Assistant ProfessorMachiko Kasai
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Microbiology Lab
Biochemistry LabFaculty of Dental Medicine, School of Dental MedicineBone metabolism, cell biology, Alzheimer's disease, genomic …
Hard Tissue Microstructure LabFaculty of Dental Medicine, School of Dental MedicineCell biology of bone, cartilage, and teeth; calcification; o…
Oral and Maxillofacial Surgery LabFaculty of Dental Medicine, School of Dental MedicineOral cancer, jaw deformities, cleft palate, odontogenic tumo…
Oral Diagnosis and Medicine LabFaculty of Dental Medicine, School of Dental MedicineDiagnostics, oral medicine diseases, oral cancer, osteomyeli…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Microscope view of Candida albicans” Korinna / CC BY 4.0 (cropped)
- How Oral Bacteria Affect Gut Bacteria: “Candida albicans colony morphology on Sabouraud dextrose agar (SDA) after 72 hours of incubation-front view” Ajay Kumar Chaurasiya / CC BY 4.0 (cropped)
- Inflammasomes and Inflammation: “Inflammasome (NIH BioArt 255)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Regulating Gene Expression with Microbial Gene Fragments: “Ribosome mRNA translation en” LadyofHats / Public domain (cropped)
- Related lab (Biochemistry Lab): “Rheumatology - Osteoporotic bone -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
- Related lab (Hard Tissue Microstructure Lab): “Bone histomorphometry” Jbakalovic / CC BY 4.0 (cropped)
- Related lab (Oral and Maxillofacial Surgery Lab): “US, Tanzanian medical professionals conduct dental surgery during Justified Accord )” U.S. Army SETAF-AF by Pfc. Alva Gonzalez / Public domain (cropped)
- Related lab (Oral Diagnosis and Medicine Lab): “Dentist Examining Patient’s Teeth with Dental Mirror” Jameswasswa / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.