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23 labs · 0 student voices
Other departments in School of Dental Medicine ›Faculties at Hokkaido University ›

Shigeru Takahashi, Professor
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The Oral Functional Anatomy Lab studies normal function and the mechanisms of disease in oral tissues. Mainly through animal experiments, the lab examines the shape and structure of tissues, with microscopy at the center of its work. Current projects include salivary gland damage and repair, the effects of soft foods on oral tissues, and how sensations from the face and mouth are transmitted. The lab's motto is "research driven by free thinking," and its range of research subjects and methods is a distinctive feature.

Makoto Funahashi, Professor
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The Oral Physiology Lab studies how oral functions such as eating behavior and taste relate to the brain (the central nervous system). Using electrophysiology and neuroscience methods, the lab investigates how the brain regulates feeding behavior, vomiting, taste, and learning. Using conditioned taste aversion, the learning process through which taste likes and dislikes arise, as a model, the lab also seeks to clarify how taste experiences relate to the expression of anxiety and fear. The lab also values joint research with clinical departments.

Kiwamu Sakaguchi, Professor
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The Oral Functional Prosthodontics Lab studies how to restore the form and function of lost teeth and oral tissues with removable dentures (complete and partial dentures) and implants. Its work includes computer analysis of the forces acting on prosthetic devices and research on new biomaterials made from carbon nanomaterials. The lab also conducts research on the relationship between occlusion (the way the teeth fit together) and the whole body, as well as clinical studies on the course and outcomes of prosthodontic treatment.

Shinichiro Kuroshima, Professor
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The Crown-Bridge and Implant Regenerative Prosthodontics Lab studies prosthodontic treatment using crowns, bridges (crown-and-bridge), and dental implants. The lab focuses on dental biology, investigating the mechanisms and treatment of medication-related osteonecrosis of the jaw (a disease in which the jawbone dies in connection with certain drugs) and the hard and soft tissues around implants. It also works on digital technology using CAD and 3D printers, and on clinical research into bruxism, temporomandibular disorders, and sleep apnea syndrome. The lab values basic and clinical research that can be fed back into actual patient care.

Yoshiaki Sato, Professor
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The Orthodontics Lab studies orthodontic treatment, which corrects the bite and tooth alignment by moving teeth and controlling jaw growth. The lab investigates, from both basic and clinical perspectives, how bone and tissue are remodeled by orthodontic force, as well as oral function, orthodontic materials, jaw deformity, and cleft lip and palate. Lab members also provide clinical care in the orthodontic department of Hokkaido University Hospital, and all graduate students receive training accredited by the Japanese Orthodontic Society.

Koichi Nakamura, Professor
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The Pediatric and Special Needs Dentistry Lab specializes in pediatric dentistry and dentistry for people with disabilities. It aims to prevent impairments of oral function caused by childhood illnesses and abnormalities, and to watch over healthy oral development and physical and mental growth. Through pediatric dental treatment, the lab's goal is to improve chewing function and support psychological development. The lab also provides appropriate, comprehensive dental care to patients whose illnesses or disabilities make dental treatment difficult.

Norio Amizuka, Professor
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The Hard Tissue Microstructure Lab studies hard tissues such as bone, cartilage, and teeth at the level of cells and tissues. Its topics are wide-ranging, including bone diseases such as osteoporosis, congenital skeletal abnormalities, the mechanism of mineralization, and the relationship between bone and conditions such as kidney disease and diabetes. In addition to light and electron microscopy, the lab uses a variety of microscopy methods, including super-resolution microscopy, micro-CT, and instruments for examining the distribution of elements. Researchers and graduate students from overseas, as well as undergraduate students, join the lab, and research is carried out with a diverse group of colleagues.

Jiwon Lee, Professor
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The Biochemistry Lab takes a molecular biochemistry approach, studying gene function, metabolism, and protein function to research how diseases arise. It investigates genes shared by osteoporosis and Alzheimer's disease, and the relationship between inflammation caused by periodontal bacteria and dementia. The lab also studies molecular mechanisms involved in bone metabolism and blood vessel formation, and works on AI-based drug discovery and bioinformatics analysis. The lab also recruits undergraduate students, who can join the journal club where English-language papers are read.

Yasuhiro Yoshida, Professor
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The Biomaterials Engineering Lab researches materials used in dental treatment (biomaterials). By imitating how the fine textures of living tissue work, it creates material surfaces to which cells attach well or that kill bacteria. It designs “phosphorylated pullulan,” a polysaccharide derivative that adheres strongly to teeth and bone, from the molecular level, and is expanding its uses to oral care products, bone substitute materials, and more. The lab aims to develop high-performance materials and medical devices that have not existed before.

Masanori Iwasaki, Professor
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The Dental Public Health Lab aims to contribute to disease prevention and health promotion through oral health. Students learn how to plan and conduct epidemiological surveys and studies, interpret the results correctly, and share them with local and international communities. The lab works closely with dentists and dental hygienists at local governments and public health centers, and together they consider how community dental health should be run. Undergraduate students, graduate students, international students, and the lab's staff interact with one another while each pursues their own research topic.
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