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Laboratory Test Development Lab
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The lab analyzes blood lipids to work on the prevention of lifestyle-related diseases and the development of new laboratory tests.

AboutAbout the lab
New clinical laboratory tests from lipid analysis.
The Laboratory Test Development Lab analyzes lipids and lipoproteins in blood to study the mechanisms and prevention of lifestyle-related diseases.
It also aims to find substances that serve as markers of disease and to develop useful clinical laboratory tests and analytical methods.
In joint research with companies in Hokkaido, the lab uses locally produced ingredients to study how foods help maintain health.
The lab is part of Professor Hui Shuping's group, which holds a monthly meeting in English to report on research progress.
Key terms
- Lipoprotein
- A particle made up of lipids and proteins that carries lipids through the blood. LDL and HDL are examples.
- Biomarker
- A substance that increases or decreases when a disease is present. It serves as a clue for diagnosis and for assessing the risk of developing a disease.
- Mass spectrometer
- An instrument that measures the mass of substances to determine the types and amounts of substances contained in a sample.
NewsLab news
A paper on a cell-based assay that uses lipid analysis to search for antioxidants has been accepted by Nutrients
A patent has been granted for a diagnostic method for non-alcoholic steatohepatitis
A student received the Young Investigator Excellent Presentation Award at the 32nd Annual Meeting of the Japanese Society of Mibyou
A master's student received the Young Investigator Excellent Presentation Award at a regular meeting of the Hokkaido Branch of the Japan Society of Clinical Chemistry
Doctoral and master's students received the Excellent Presentation Award at the general meeting of the Hokkaido Branch of the Japanese Society of Laboratory Medicine
ResearchResearch themes
The lab analyzes lipids and lipoproteins in blood, aiming to clarify the pathology and prevention of lifestyle-related diseases and to develop useful clinical laboratory tests. It also draws on its expertise in clinical laboratory science and health sciences to study the functionality of foods.
*Illustrative imageLifestyle-related diseases viewed through lipids
The lab analyzes the lipids and proteins of lipoproteins in blood (LDL and HDL) and examines how they change in people with disease. It aims to clarify the pathology of non-alcoholic steatohepatitis, chronic kidney disease, and arteriosclerosis, and to establish ways to prevent them.
*Illustrative imageDeveloping clinical laboratory technologies
This research focuses on lipids and lipoproteins to search for disease biomarkers and to develop useful clinical laboratory tests and analytical methods. It uses a variety of instruments, such as mass spectrometers and automated biochemical analyzers.
*Illustrative imageResearch on food functionality
The lab scientifically investigates new functions of foods and the evidence behind them, with the aim of helping maintain health. In joint research with companies in Hokkaido, it conducts studies using locally produced ingredients.
MembersFaculty
The members of the Laboratory Test Development Lab are faculty, JSPS Research Fellows, and doctoral, master's, and undergraduate students.As of 2025
- Associate ProfessorToshihiro Sakurai
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Lipemic sérum ex1” J3D3 / CC BY-SA 4.0 (cropped)
- Lifestyle-related diseases viewed through lipids: “Liver steatosis fatty change” Laboratory of Experimental Pathology, Division of Intramural Research, NIEHS (NIH) / Public domain (cropped)
- Developing clinical laboratory technologies: “Applied Biosystems 4000 QTrap Mass Spectrometer (detail) (5)” Hey Paul from Sacramento, CA, USA / CC BY 2.0 (cropped)
- Research on food functionality: “Tokachi plain 02” satoshi sawada / CC BY 2.0 (cropped)
- Related lab (Cellular Metabolic Chemistry Lab): “Adipocytes Lipid Droplets Oil Red O Staining Rkott 2023” Rkott / CC BY-SA 4.0 (cropped)
- Related lab (Biomedical Science and Engineering Lab): “Beta radiation in a cloud chamber” Nuledo / CC BY-SA 4.0 (cropped)
- Related lab (Pathological and Immunological Laboratory Science Lab): “Renal corpuscle” Ed Uthman (Pathologist) / CC BY-SA 2.0 (cropped)
- Related lab (Social Medical Informatics Lab): “Satellite image of Hokkaido, Japan in May 2001” NASA / Public domain (cropped)
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