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生命分子機構
Showing the original Japanese · View translation
オートファジーと液－液相分離から、生命現象を分子レベルで解き明かす研究室。
AboutAbout the lab
オートファジーと相分離を、分子レベルで解き明かす。
生命分子機構分野は、
タンパク質が
複雑な
遺伝子病制御研究所の
Key terms
- オートファジー
- 細胞が
自分の 中の タンパク質や 小器官などを 包み込み、 分解する しくみ。 細胞の 状態を 保つ 働きを もつ - 液－液相分離
- タンパク質や
核酸が 寄り集まり、 細胞の 中に 膜の ない液体状の 集まりを つくる 現象 - AlphaFold2
- アミノ酸の
並びの 情報だけから、 タンパク質の 立体構造を 高い 精度で 予測する プログラム
NewsLab news
横浜市立大学などとの
共同研究で、 脂質分解酵素Atg15が 膜を 安全に 壊す仕組みを 解明 大阪大学などとの
共同研究で、 細胞内の 新しい 温度センサーを 発見 名古屋大学などとの
共同研究で、 膜タンパク質の 折り畳みを 助ける 品質管理機構を 発見 順天堂大学などとの
共同研究で、 神経細胞を 守る 新しい 品質管理機構を 発見 東京科学大学との
共同研究で、 オートファジーの 初期過程を 試験管内で 再現
ResearchResearch themes
液－液相分離の
*Illustrative imageオートファジーのしくみ
数十種類の
*Illustrative image液－液相分離が制御する生命現象
タンパク質や
*Illustrative image立体構造にもとづく働きの解明
これまで
*Illustrative imageタンパク質から見る睡眠のしくみ
筑波大学と
MembersFaculty
生命分子機構分野の
- Professor野田 展生
- Associate Professor藤岡 優子
- Project Lecturer辻 琢磨
- Assistant Professor能代 大輔
- Project Assistant Professor武田 英吾
- Project Assistant Professor西奈美 卓
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The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Autophagosomes” Genericuser / Public domain (cropped)
- オートファジーの
しく み: “1ugm bio r 500” Hannes Röst / Public domain (cropped) - 液－液相分離が
制御する 生命現象: “HeLa-Tubulin-HSP60-Fibrillarin-DNA” GerryShaw / CC BY-SA 4.0 (cropped) - 立体構造にもと
づく 働きの 解明: “Cryo-EM structure of bovine phosphodiesterase 6 bound to IBMX - 8ULG” Aplin C, Cerione RA / CC0 (cropped) - タンパク質から
見る 睡眠の しく み: “Drosophila melanogaster - side (aka)” André Karwath aka Aka / CC BY-SA 2.5 (cropped) - Related lab (心臓血管外科学): “A moulage of heart” Realmastery / CC BY-SA 4.0 (cropped)
- Related lab (分子神経免疫学): “Fluorescently Labeled Microglia in a Coronal Brain Section from a C57 Mouse” Syed07 / CC BY 4.0 (cropped)
- Related lab (組織細胞学): “Z MaxProjection of MediumSpinyNeurons Gpr101Cre dtTomato” Bruttokolliko / CC BY-SA 4.0 (cropped)
- Related lab (幹細胞生物学): “"Forest of memory"” RebecaCuesta / CC BY-SA 4.0 (cropped)
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