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Gastroenterological Surgery II Lab
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A surgical lab that takes on difficult-to-treat cancers of the esophagus, stomach, biliary tract, and pancreas through surgical treatment.
AboutAbout the lab
People gather, and everyone gets better
The lab studies the surgical treatment of difficult-to-treat cancers such as esophageal, gastric, biliary tract, and pancreatic cancer.
Its mission is to contribute to the greatest happiness of patients by reforming surgical care based on basic and clinical research.
The whole lab also works on developing endoscopic surgery, which puts less strain on the body, and on “surgical education,” the study of how to train surgeons' skills.
The lab is mainly in charge of the all-department clinical clerkship (general surgery) for the Department of Medicine, and also holds “Somei Juku,” a surgical skills training course for medical students.
Key terms
- Endoscopic surgery
- Surgery performed by making small openings in the body and inserting a camera and specialized instruments. The incisions are small and the burden on the body is low.
- EMT
- Epithelial-mesenchymal transition. A mechanism by which cancer cells change their characteristics and gain the ability to invade surrounding tissue.
- Cancer-testis antigen
- A marker found abundantly on cancer cells and almost absent from normal cells other than those of the testis. It serves as a target for immunotherapy.
NewsLab news
Recruiting participants for the 62nd Somei Juku, a surgical skills training course for medical students
The all-department clinical clerkship (general surgery) run by the lab received the Department of Medicine's Outstanding Course Award (Top Prize)
Prof. Hirano received the FY2025 (Reiwa 7) Hokkaido Science and Technology Award
ResearchResearch themes
The lab aims to establish comprehensive treatments that incorporate surgery for difficult-to-treat cancers such as esophageal, biliary tract, and pancreatic cancer, and to develop new surgical treatments that put less strain on the body. It also conducts research on surgical education for training surgeons.
*Illustrative imageSurgical Treatment of Biliary Tract Cancer
For biliary tract cancer, where complete surgical removal is the only way to aim for a cure, the lab studies how to select the patients suited for surgery and the appropriate procedure, adjuvant therapy combined with surgery, and patterns of tumor spread. It is also pursuing basic research on the mechanism by which cancer invades surrounding tissue and metastasizes (EMT).
*Illustrative imageDeveloping Endoscopic Surgery and Instruments
The lab is developing surgical techniques to perform endoscopic surgery for esophageal cancer and hepato-biliary-pancreatic cancers safely and reliably, as well as new instruments to support surgery.
*Illustrative imageCancer Immunotherapy
The lab studies immunotherapies such as cancer vaccines targeting cancer-testis antigens. Using tissue removed during surgery for esophageal, pancreatic, and biliary tract cancer, it also examines the function of immune cells around the tumor.
*Illustrative imageSurgical Education
To help young surgeons gain solid skills and confidence, the lab studies undergraduate and postgraduate surgical education curricula and new teaching methods. It also works on AI-based assessment of surgical skills, the effects of simulation training, and surveys of burnout among surgeons.
MembersFaculty
The lab's members consist of faculty, visiting faculty, medical staff, research fellows, specially appointed specialist staff, data managers, and secretaries. The faculty include physicians who also serve as Clinical Associate Professor and Clinical Lecturer in Gastroenterological Surgery II at Hokkaido University Hospital. Faculty from the Faculty of Health Sciences also take part in providing guidance.As of 2026
- ProfessorSatoshi Hirano
- Associate ProfessorToshiaki Shichinohe
- Assistant Professor (Center for Advanced Medical Technology Education, Research and Development)Soichi Murakami
- Clinical Associate ProfessorToshimichi Asano
- Assistant ProfessorYoshitsugu Nakanishi
- Assistant ProfessorAya Matsui
- Assistant ProfessorKimitaka Tanaka
- Project Assistant ProfessorMasataka Wada
- Assistant ProfessorShintaro Takeuchi
- Project Assistant ProfessorHideyuki Wada
- Project Assistant ProfessorHironobu Takano
- Assistant Professor (Clinical Simulation Center)Saseem Poudel
- Professor, Division of Fundamental Nursing, Graduate School of Health SciencesTakehiro Noji
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Instruments for laparoscopic Hernia Operation” Anpol42 / CC BY-SA 3.0 (cropped)
- Surgical Treatment of Biliary Tract Cancer: “Cholangiocarcinoma - high mag” Nephron / CC BY-SA 3.0 (cropped)
- Developing Endoscopic Surgery and Instruments: “Laparoscopic stomach surgery” Samuel Bendet, US Air Force / Public domain (cropped)
- Cancer Immunotherapy: “Killer T cells surround a cancer cell” The National Institutes of Health / Public domain (cropped)
- Surgical Education: “Chirurgischer Knoten 14” Werneuchen / Public domain (cropped)
- Related lab (Gastroenterological Surgery I Lab): “3D printed liver model - tumor” Jan Witowski / CC BY-SA 4.0 (cropped)
- Related lab (Pathogenic Microbiology Lab): “HIV-infected H9 T cell2” NIAID/NIH / Public domain (cropped)
- Related lab (Cancer Genomic Medicine Lab): “DNA Nanoball sequencing flow cell” Suspencewl / CC0 (cropped)
- Related lab (Neurology Lab): “Neurological tools” Ali Raheem / CC BY-SA 3.0 (cropped)
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