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Natural Product Synthesis Lab
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The lab develops synthetic strategies to assemble complex natural products concisely.

AboutAbout the lab
Passing on and creating knowledge through natural product synthesis
The Natural Product Synthesis Lab studies the synthesis of natural organic compounds (natural products) made by plants and microorganisms.
Natural products have supported people's lives as substances useful in medicines, agrochemicals, fragrances, and more.
The lab works on developing new synthetic strategies to assemble complex natural products with strong biological activity by concise methods.
The lab was launched in November 2023 through the merger of the Pharmaceutical Manufacturing Chemistry Lab and the Organic Chemistry for Drug Discovery Lab.
Key terms
- Natural product
- An organic compound made by living things such as plants and microorganisms. Many serve as the basis for drugs
- Polycyclic
- A molecular shape in which many ring-shaped structures are connected. Often seen in natural products
- Analog
- A similar compound made by changing part of the structure while retaining the skeleton of the original compound
NewsLab news
A master's student received the Student Excellent Presentation Award at the 152nd Meeting of the Hokkaido Branch of the Pharmaceutical Society of Japan
Assistant Professor Shimakawa received the 41st Inoue Research Award for Young Scientists
Assistant Professor Shimakawa received the Encouragement Award at the 65th Symposium on the Chemistry of Natural Products, Japan
A master's student received the Excellent Poster Presentation Award at the 56th Summer Study Meeting for Young Peptide Researchers
ResearchResearch themes
Building on synthetic organic chemistry, the lab aims to contribute to the creation of new drugs. It studies methods to synthesize complex natural products with strong biological activity efficiently and flexibly.
View More ↗MembersFaculty
The members of the Natural Product Synthesis Lab consist of faculty, doctoral, master's, and undergraduate students, and administrative staff.As of 2026
- Professor長友 優典
- Associate ProfessorMizuki Watanabe
- Assistant Professor島川 典
- Assistant Professor祷 雄太
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Rotationsverdampfer ohne Vakuumpumpe” HaJo88 / CC BY-SA 4.0 (cropped)
- Assembling complex natural products concisely: “Paclitaxel-from-hydrate-xtal-Mercury-3D-bs” Ben Mills / Public domain (cropped)
- Related lab (Precision Synthetic Chemistry Lab): “CSIRO ScienceImage 10606 High vacuum apparatus” division, CSIRO / CC BY 3.0 (cropped)
- Related lab (Infection and Oncology Lab, Division of Pathophysiology, Institute for Genetic Medicine): “Ulcer-causing Bacterium (H.Pylori) Crossing Mucus Layer of Stomach” Illustration Credit: Zina Deretsky, National Science Foundation / Public domain (cropped)
- Related lab (Molecular Cell Biology Lab): “Vesicular Stomatitis Virus (VSV) particles (orange) found in extracellular space and budding from the plasma membrane of infected cells (teal)” NIAID / CC BY 2.0 (cropped)
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