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Osawa Lab
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A lab that integrates nutrition and omics data to shape the future of cancer treatment.
AboutAbout the lab
The future of cancer treatment, through nutriomics
Osawa Lab aims to develop new cancer therapies from the perspective of "nutriomics," which integrates nutrition and omics data.
It has become clear that the harsh environment surrounding cancer cells (the tumor microenvironment) promotes cancer progression.
The lab integrates multiple layers of omics information, from genes to metabolites, to analyze cancer cells within the tumor microenvironment.
The lab believes that overcoming cancer requires research that spans medicine, biology, engineering, and chemistry.
Key terms
- Omics
- A research approach that comprehensively examines the molecules inside cells, such as genes, proteins, and metabolites, all together
- Tumor microenvironment
- The environment surrounding cancer cells. It is often harsh for cancer cells, for example with low levels of oxygen and nutrients
- Oncometabolite
- A metabolite that accumulates inside cancer cells and promotes cancer growth, metastasis, and other processes
NewsLab news
Paper from joint research with Zeon Corporation accepted by Scientific Reports
Paper from joint research accepted by Cancer Medicine
Paper from joint research with Nishimasu Lab accepted by Nature Communications
Master's student wins Best Poster Award at the Cancer and Metabolism Research Meeting
Master's student's paper published in Cell Reports
ResearchResearch themes
The lab integrates genomic, epigenomic, transcriptomic, proteomic, and metabolomic information on cancer cells within the tumor microenvironment, and aims to develop new cancer therapies from the perspective of nutriomics.
*Illustrative imageSearching for metabolites that worsen cancer
Cancer cells are known to accumulate metabolites that contribute to growth and metastasis (oncometabolites) in response to harsh environments. The lab searches for oncometabolites that are not yet known and investigates their functions.
*Illustrative imageCancer cells adapting to harsh environments
Cancer cells become malignant in environments that are low in oxygen and nutrients and have turned acidic. The lab aims to elucidate the mechanisms by which cancer cells adapt their metabolism, in multiple layers, to the three major nutrients: carbohydrates, lipids, and amino acids.
*Illustrative imageDeveloping treatments through nutriomics
Starting from nutrition, the lab integrates and analyzes omics information such as genes, proteins, and metabolites. It aims to clarify the molecular mechanisms involved in cancer progression and lead to the development of new cancer therapies.
MembersFaculty
Osawa Lab members include faculty, project researchers, visiting researchers, collaborative researchers, designers, administrative assistants, doctoral and master's students, and trainees and exchange trainees.As of 2026
- Associate ProfessorTsuyoshi OsawaPublications ↗
- Project LecturerKazuyuki YamagataPublications ↗
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Breast cancer cell (2)” National Cancer Institute
（撮影者不明） / Public domain (cropped) - Searching for metabolites that worsen cancer: “Metabolomic analyses ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Cancer cells adapting to harsh environments: “Breast cancer (ductal carcinoma) (1)” National Cancer Institute
（撮影者不明） / Public domain (cropped) - Developing treatments through nutriomics: “Fluorescence microscopy of the oral cancer cells” Korinna / CC BY 4.0 (cropped)
- Related lab (Neuronal Cell Biology Lab (Hirabayashi Lab)): “Нейрон коры с множеством дендритных шипиков” Sergb95 / CC BY-SA 4.0 (cropped)
- Related lab (Ikeuchi Lab): “Human Cerebral Organoids ( )” NIAID / CC BY 2.0 (cropped)
- Related lab (Sando Lab): “Robot arm handles an assay plate” National Institute of Allergy and Infectious Diseases / Public domain (cropped)
- Related lab (Suzuki Lab): “3d tRNA” Vossman / CC BY-SA 3.0 (cropped)
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