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19 labs · 16 student voices
Other departments in Faculty of Engineering ›Faculties at The University of Tokyo ›

Yusuke Hirabayashi, Associate Professor
Bio & Life Sciences3 student voices
The Neuronal Cell Biology Lab studies why animals are able to have sophisticated mechanisms for homeostasis and learning. Molecular reactions occur constantly in the body, but much is still unknown about where, when, and how they take place. The lab's central themes are the formation and functional regulation of neural circuits, and interorganelle interactions in mammalian cells. The lab uses genetic manipulation and analysis of cells and tissues with fluorescence and electron microscopy.

Tsutomu Suzuki, Professor
Bio & Life Sciences2 student voices
The Suzuki Lab focuses on the chemical modifications that RNA undergoes and studies the roles of RNA in a wide range of life phenomena. RNA is subject to many kinds of modifications after it is synthesized, so its functions can no longer be explained by genome sequence information alone. Abnormalities in RNA modifications can cause human diseases, and the concept of "RNA modopathy," proposed by the lab, is becoming established. Combining molecular biology, biochemistry, and analytical chemistry, the lab also develops its own devices for isolating RNA and its own mass spectrometry techniques.

Kyoko Nozaki, Professor
Chemistry & Catalysis2 student voices
The Nozaki Lab studies methods for making organic compounds and polymers, centered on catalytic reactions. The lab also explores the functions of the new substances obtained through its original methods. From many perspectives, such as whether the research is elegant and whether it truly has the potential to benefit society, the lab pursues "what is truly interesting." The lab takes pride in the breadth of its research subjects and the versatility of its members.

Takamasa Sakai, Professor
Materials & Nanotech2 student voices
The Sakai Lab advances "precision gel science," aiming to put hydrogels to medical use on the basis of firm scientific principles. A gel is a material in which a three-dimensional polymer network holds a liquid. Hydrogels, which contain water, are found in familiar items such as soft contact lenses, diapers, and jelly. Although gels are familiar materials, many mysteries about them still remain, and the lab seeks to solve them using gels with a controlled structure. Medical applications are pursued in joint research with institutions such as the University of Tokyo Hospital, under the guidance of clinicians.

Hiroshi Nishimasu, Professor
Bio & Life Sciences1 student voices
The Nishimasu Lab studies the molecular mechanisms by which proteins and nucleic acids (DNA and RNA) function, based on their three-dimensional structures. For example, the protein Cas9 pairs with a guide RNA to cut targeted DNA, and it has been applied in technologies such as genome editing. The lab examines the shapes of molecules using methods such as X-ray crystallography and cryo-electron microscopy, and uses that information to create new genome editing tools. The lab is also taking on the search for new enzymes that have not yet been discovered.

Kouhei Tsumoto, Professor
Bio & Life Sciences1 student voices
Tsumoto Lab studies how biomolecules such as proteins bind to one another. Using a variety of pairings as subjects, including antibodies and antigens and receptors and the molecules that bind to them, the lab investigates the strength of binding and the mechanisms by which molecules select their partners. The lab combines experiments such as methods that measure heat exchange (calorimetry) and crystal structure analysis with computational calculations in its analyses. Based on the findings, the lab takes on the design of proteins and small molecules, aiming at applications in medicine and materials.

Yoshimitsu Itoh, Associate Professor
Materials & Nanotech1 student voices
The Molecular Interface Engineering Lab studies new molecules that act on interfaces, the boundaries where substances meet. Interfaces make up only a small part of a material as a whole, yet their influence is so great that one could say most of a material's properties and functions are determined at the interface. Using synthetic organic chemistry and polymer chemistry, the lab designs and synthesizes molecules, aiming to develop unprecedented ways of making materials and new functional materials. Recently, the lab has been working on porous polymer membranes that are lightweight yet rigid, and on materials that make use of new properties of amides.

Daisuke Kawaguchi, Project Professor
Chemistry & Catalysis1 student voices
The Fluorine Organic Chemistry Lab studies the properties of fluorine-containing molecules and polymers and applies them to new materials. Established in the Department of Chemistry and Biotechnology with funding from AGC Inc., the lab is a Social Cooperation Program that conducts research in collaboration with industry. Making use of handling techniques for fluorinated gases, which have rarely been used in academic research, the lab pursues material design with a high degree of freedom. The lab also aims to develop drug delivery systems that combine the characteristics of fluorine-containing molecules.

Akimitsu Okamoto, Professor
Bio & Life Sciences1 student voices
The Okamoto Lab studies how biopolymers such as nucleic acids (DNA and RNA) and proteins are involved in biological phenomena. Bringing the approach of synthetic organic chemistry into biology and genetics research, the lab designs and synthesizes artificial biopolymers with special functions. The lab also develops new chemical systems that can identify, modify, and visualize a single component or even a single atom within a biopolymer. Its work combines organic synthesis, photochemistry, state-of-the-art spectroscopy, and biological experiments.

Tsuyoshi Osawa, Associate Professor
Medicine & Healthcare1 student voices
Osawa Lab aims to develop new cancer therapies from the perspective of "nutriomics," which integrates nutrition and omics data. It has become clear that the harsh environment surrounding cancer cells (the tumor microenvironment) promotes cancer progression. The lab integrates multiple layers of omics information, from genes to metabolites, to analyze cancer cells within the tumor microenvironment. The lab believes that overcoming cancer requires research that spans medicine, biology, engineering, and chemistry.
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