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Radiation Animal Science Lab
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The lab uses animal disease models to explore the mechanisms and treatments of allergies and cancer.
AboutAbout the lab
Uncovering how disease works from a whole-organism perspective
The Radiation Animal Science Lab creates animal disease models to study how diseases arise and progress.
Its subjects range from allergic diseases such as food allergy, asthma, and atopic dermatitis to the growth and metastasis of cancer.
The central theme is clarifying how lipid mediators regulate inflammation and applying this knowledge to treatment.
The lab was founded after the Great East Japan Earthquake to investigate the effects on the body of long-term exposure to low-dose radiation.
Key terms
- Disease model
- An animal made to develop a condition resembling a human disease, so that its mechanisms and treatments can be studied
- Lipid mediator
- A substance made from lipids such as fatty acids that regulates bodily responses such as inflammation. Prostaglandins are a representative example
- Mast cell
- A type of immune cell that triggers allergic reactions. The Japanese name for it, literally "obesity cell" (肥満細胞), has nothing to do with gaining weight
NewsLab news
Reported a urinary marker that distinguishes anaphylaxis during surgery, in collaboration with Gunma University and the University of Toyama
Reported that abnormalities in gut microbiota and lipid metabolism may be involved in allergic diseases in dogs
Developed a test kit that can assess the state of food allergy from urine
Recruiting master's and doctoral students for the Veterinary Pharmacology Lab
Developed a system that uses AI to visualize itching in mice
ResearchResearch themes
The lab creates animal disease models to clarify the mechanisms by which diseases develop and progress. Alongside elucidating physiological responses, a major goal is developing diagnostics and treatments for human diseases.
*Illustrative imageLipid mediators that regulate inflammation
The lab regards lipid mediators such as prostaglandins as factors that create the setting for physiological and pathological reactions. It is clarifying how they control inflammation and aims to apply this to the treatment of disease.
*Illustrative imageDiagnosis and treatment of food allergy
The lab is searching urine and feces for marker substances that appear as food allergy develops. It is also developing treatments that make use of the mechanism by which mast cells increase in number.
*Illustrative imageCancer, blood vessels, and immune cells
Focusing on how cancer cells interact with the surrounding blood vessels and immune cells, the lab investigates the mechanisms of carcinogenesis, tumor growth, and metastasis. It is working on drugs that inhibit angiogenesis and on immune cell therapies.
*Illustrative imageAnalyzing animal behavior with AI
Using image analysis and AI, the lab is developing methods to assess the vital signs and emotional states of laboratory animals without anesthesia or restraint. These methods are used to analyze models of allergy, depression, and dementia.
MembersFaculty
The members of the Radiation Animal Science Lab consist of faculty, project researchers, joint research fellows in agriculture, secretaries, and doctoral, master's, and undergraduate students.As of 2026
- Associate ProfessorTakahisa MurataPublications ↗
- Project LecturerNanae NagataPublications ↗
- Project Lecturer小林 幸司
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Individually cage for lab mice” Karol Głąb (Karol007) / CC BY-SA 3.0 (cropped)
- Lipid mediators that regulate inflammation: “The surface of highly curved lipid bilayer” Semen Yesylevskyy / CC BY 4.0 (cropped)
- Diagnosis and treatment of food allergy: “Mast cells in bone marrow” Vortioxetine / CC BY-SA 4.0 (cropped)
- Cancer, blood vessels, and immune cells: “Tumor angiogenesis” Mjeltsch / CC BY-SA 4.0 (cropped)
- Analyzing animal behavior with AI: “Mouse in a cage” Ciotu Cosmin / CC BY-SA 4.0 (cropped)
- Related lab (産業技術総合研究所): “Brainbow (Smith 2007)” Stephen J Smith / CC BY 3.0 (cropped)
- Related lab (応用免疫学研究室): “Leishmania major promastigotes” Abanima (ru.wikipedia) / CC BY-SA 3.0 (cropped)
- Related lab (応用遺伝学研究室): “GFP Mice 01” Ingrid Moen, Charlotte Jevne, Jian Wang, Karl-Henning Kalland, Martha Chekenya, Lars A Akslen, Linda Sleire, Per Ø Enger / CC BY 2.0 (cropped)
- Related lab (東京大学大学院農学生命科学研究科附属牧場
（Animal Resource Science Center） （山内啓太郎研究室） ): “Cattle grazing, Fillmore County, Minnesota” Y1997xf11 / Public domain (cropped)
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