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AIST Lab
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The lab uses animal models to study the neural circuits in the brain that underlie learning and memory.

AboutAbout the lab
How does the brain learn and adapt?
The Uematsu Lab uses animal models to study the brain mechanisms involved in learning and memory.
The lab aims to uncover how the brain works as animals learn in response to pleasant and unpleasant stimuli.
It also studies how learned memories are updated so that animals can adapt when the environment or conditions change.
The lab's faculty member is a Senior Researcher at the National Institute of Advanced Industrial Science and Technology (AIST) and concurrently serves as an Associate Professor in the Department of Animal Resource Sciences at the University of Tokyo.
Key terms
- Animal model
- An animal in which a condition closely resembling a human one is reproduced, used to study how the human body and brain work
- Neural circuit
- A pathway for information in the brain, formed by connections among nerve cells (neurons)
- Traumatic memory
- The memory of an event involving intense fear or stress, such as an accident or disaster
ResearchResearch themes
Using animal models, the lab aims to uncover how the brain works as animals respond to pleasant and unpleasant stimuli and learn from them. It also studies how learned memories are updated and how animals adapt as the environment or conditions change.
*Illustrative imageExtinction of Traumatic Memory and Neural Circuits
Among the neural circuits involved in learning and extinction, the lab studies which circuits are important for methods that extinguish traumatic memories.
*Illustrative imageSex Differences in Learning Circuits
The lab has found that the neural circuits involved in learning differ between the sexes. It studies how these sex differences arise in neural circuits during development.
*Illustrative imageEarly-Life Experience and Learning
Using animal models, the lab seeks to understand whether stress in early life changes the way traumatic memories are processed.
*Illustrative imageHabituation to Bitterness and Nutrient Information
The lab seeks to explain, from a neuroscience perspective, why people come to like beer and coffee. It also studies how information about nutrients is conveyed to the brain.
MembersFaculty
The Uematsu Lab consists of the faculty member, technical staff, and doctoral and master's students.
- Associate ProfessorAkira Uematsu
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Brainbow (Smith 2007)” Stephen J Smith / CC BY 3.0 (cropped)
- Extinction of Traumatic Memory and Neural Circuits: “CA2 amigo2 eGFP mouse” Dudek, Serena; Curuana, Douglas; Carstens, Kelly / CC BY-SA 3.0 (cropped)
- Sex Differences in Learning Circuits: “Кортикальный нейрон новорожденной мыши in vitro” Sergb95 / CC BY-SA 4.0 (cropped)
- Early-Life Experience and Learning: “ChimericMouseWithPups” Staff at NIMH's Transgenic Core Facility / Public domain (cropped)
- Habituation to Bitterness and Nutrient Information: “Coffee cup surrounded by coffee beans” Petr Kratochvil / CC0 (cropped)
- Related lab (Radiation Animal Science Lab): “Individually cage for lab mice” Karol Głąb (Karol007) / CC BY-SA 3.0 (cropped)
- Related lab (Applied Genetics Lab): “GFP Mice 01” Ingrid Moen, Charlotte Jevne, Jian Wang, Karl-Henning Kalland, Martha Chekenya, Lars A Akslen, Linda Sleire, Per Ø Enger / CC BY 2.0 (cropped)
- Related lab (Yamanouchi Lab): “Cattle grazing, Fillmore County, Minnesota” Y1997xf11 / Public domain (cropped)
- Related lab (Applied Immunology Lab): “Leishmania major promastigotes” Abanima (ru.wikipedia) / CC BY-SA 3.0 (cropped)
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