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Molecular and Cellular Biology Lab
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A lab that investigates the effects of chemical substances by using gene responses as clues.
AboutAbout the lab
Looking at the environment and chemical substances through gene responses.
The lab of Associate Professor Shinichi Ogata studies the DNA damage response in plants and the evaluation of chemical substances using gene responses as indicators.
In addition to its work on the plant DNA damage response, the lab studies alternatives to animal testing using higher plants, and methods for evaluating skin-sensitizing substances in vitro.
Its research themes also include the effects of cosmetic ingredients on reef-building corals and a new system for evaluating endotoxin.
Key terms
- Skin sensitization
- Skin sensitization: the property of a chemical substance that can cause allergic contact dermatitis after it touches the skin.
- in vitro
- In vitro: studying something using test tubes or cultured cells, rather than living animals.
- Alternatives to animal testing
- Alternatives to animal testing: test methods that use cells, plants, or other materials to serve the same purpose as experiments on animals.
ResearchResearch themes
The lab investigates how plants and cells respond to DNA damage and chemical substances. It also works on alternatives to animal testing and on building systems for evaluating chemical substances.
*Illustrative imageEffects of cosmetic ingredients on corals
Using molecular biology methods, the lab investigates how cosmetic ingredients affect reef-building corals. This work is carried out as contract research.
*Illustrative imageA new system for evaluating endotoxin
The lab is working on building a new system for evaluating endotoxin.
*Illustrative imageIn vitro evaluation system for skin sensitization
The lab is working on building a system that uses gene responses as indicators to evaluate skin-sensitizing substances in vitro.
*Illustrative imageAlternatives to animal testing using plants
The lab studies test methods that use higher plants and could replace animal experiments.
MembersFaculty
- Associate ProfessorShinichi Ogata
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Rotary Cell Culture System” NASA / Public domain (cropped)
- Effects of cosmetic ingredients on corals: “Coral reef with healthy corals and corals with signs of bleaching” Unidentified NOAA photographer / Public domain (cropped)
- A new system for evaluating endotoxin: “Limulus polythemus 2” Karelj / Public domain (cropped)
- In vitro evaluation system for skin sensitization: “Skin model” Scivit / CC BY-SA 4.0 (cropped)
- Alternatives to animal testing using plants: “Plant Tissue Culture Lab - Atlanta Botanical Garden” Daderot / CC BY-SA 4.0 (cropped)
- Related lab (Amemiya Lab): “Belousov Zhabotinsky reaction ( )” Stephen Morris from Toronto, Canada / CC BY 2.0 (cropped)
- Related lab (Developmental Biology Lab): “Eleutherodactylus planirostris embryos” Alex Abair / CC BY 4.0 (cropped)
- Related lab (Chemistry and Environmental Education Lab): “Colorful yarn dyed using plant, nut and insect dyes. (282dc37b-99b8-4eab-868a-e8b1023da21d)” NPS / Public domain (cropped)
- Related lab (Biophysical Chemistry and Structural Life Chemistry Lab): “Rhodopsin” AtikaAtikawa / CC BY-SA 4.0 (cropped)
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