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Amemiya Lab
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A lab that studies the rhythms of cell metabolism and how they synchronize.
AboutAbout the lab
Exploring oscillation and synchronization in chemistry and life.
The Amemiya Lab studies phenomena in which chemical reactions and reactions inside cells change periodically over time or move in unison.
In addition to nonlinear chemical reactions, the lab investigates glycolytic oscillations in cancer cells and synchronization between cells.
It is also extending its research to metabolic oscillations in astrocytes, the cells that make up the brain.
Key terms
- Glycolytic oscillation
- A phenomenon in which the reactions that break down sugar inside cells to obtain energy alternately strengthen and weaken at a regular rhythm
- Synchronization
- When the oscillation rhythms of separate cells or reactions come to move in unison
- Nonlinear chemical reaction
- A chemical reaction whose progress is not simply proportional to the amounts of the reacting substances, and which shows complex changes such as oscillation
ResearchResearch themes
The lab investigates oscillation, in which a reaction changes periodically over time, and synchronization, in which multiple reactions fall into the same rhythm, from chemical reactions to cell metabolism. It combines experiments with mathematical models and keeps applications in view.
*Illustrative imageDynamics of Nonlinear Chemical Reactions
The lab studies how chemical reactions, biochemical reactions, and processes of material formation change over time (reaction dynamics), and explores applications in science and engineering.
Intracellular Oscillations and Synchronization Between Cells
The lab studies glycolytic oscillations in cancer cells and synchronization between cells. Working with cells such as HeLa cells, it also has applications to diagnosing malignancy in view.
*Illustrative imageMetabolic Oscillations in Brain Cells and Alzheimer's Disease
The lab measures glucose metabolism in astrocytes, which make up the brain, as glycolytic oscillations and studies its dynamics. It is exploring the possibility of leading to a method for very early diagnosis of Alzheimer's disease.
MembersFaculty
- ProfessorTakashi Amemiya
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Belousov Zhabotinsky reaction ( )” Stephen Morris from Toronto, Canada / CC BY 2.0 (cropped)
- Dynamics of Nonlinear Chemical Reactions: “Belousov Zhabotinsky reaction ( )” Stephen Morris from Toronto, Canada / CC BY 2.0 (cropped)
- Metabolic Oscillations in Brain Cells and Alzheimer's Disease: “Mouse brain cells” Cody Siciliano / CC BY-SA 4.0 (cropped)
- Related lab (Biophysical Chemistry and Structural Life Chemistry Lab): “Rhodopsin” AtikaAtikawa / CC BY-SA 4.0 (cropped)
- Related lab (Molecular and Cellular Biology Lab): “Rotary Cell Culture System” NASA / Public domain (cropped)
- Related lab (Misumi Lab): “Artistic Crystallization, Side View” Paolo Infante / CC BY-SA 4.0 (cropped)
- Related lab (Takagaki Lab): “Plastic waste” Ka23 13 / CC BY-SA 4.0 (cropped)
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