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Developmental Biology Lab
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A lab that explores the development of primordial germ cells and the mechanisms behind testicular tumors.
AboutAbout the lab
From germ cell development to testicular tumors.
The lab of Associate Professor Atsushi Suzuki studies the development of primordial germ cells in the field of developmental biology.
The lab has published papers on RNA-binding proteins such as Dead end1 and NANOS2, which act as germ cells develop.
A 2023 paper from the lab reported that loss of Dead end1 leads to testicular teratoma.
Using mice, the lab investigates the mechanisms by which testicular teratoma arises.
Key terms
- Primordial germ cells
- Primordial germ cells: cells that appear during the embryonic stage and later become sperm or eggs.
- Testicular teratoma
- Testicular teratoma: a type of tumor that forms in the testis. This lab studies the mechanisms by which it develops.
- RNA-binding protein
- RNA-binding protein: a protein that binds to RNA and is involved in how that RNA is handled.
ResearchResearch themes
The lab investigates how primordial germ cells develop in the testis and what happens when that development goes wrong. It is currently working to clarify the mechanisms by which testicular teratoma arises.
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MembersFaculty
- Associate ProfessorAtsushi Suzuki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Eleutherodactylus planirostris embryos” Alex Abair / CC BY 4.0 (cropped)
- Mechanisms of testicular teratoma: “Epidermoid cyst of testis -- low mag” Nephron / CC BY-SA 3.0 (cropped)
- Related lab (Molecular and Cellular Biology Lab): “Rotary Cell Culture System” NASA / Public domain (cropped)
- Related lab (Misumi Lab): “Artistic Crystallization, Side View” Paolo Infante / CC BY-SA 4.0 (cropped)
- Related lab (Okazaki Lab): “Rust on iron” Laitr Keiows / CC BY-SA 3.0 (cropped)
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