LAB LOGA page on LabLog, a review site (not the lab's official page)
Human Disease Model Lab
Machine-translated · View original
A research team that uses humanized mice to uncover how blood and the immune system work, with the aim of overcoming leukemia.
AboutAbout the lab
From the origin of blood to overcoming leukemia.
The Human Disease Model Research Team uses humanized mice to study how blood and immune cells are produced.
The team seeks to clarify the process by which the most undifferentiated hematopoietic stem cells give rise to a wide variety of blood and immune cells.
By investigating why leukemia relapses and what kind of treatment can overcome relapse, the team aims to understand and overcome leukemia.
The team is part of the RIKEN Center for Integrative Medical Sciences (Yokohama). As a cooperative graduate school program with Chiba University, students can earn a degree while conducting research here.
Key terms
- Humanized Mouse
- Humanized mouse: a mouse transplanted with human cells so that human blood and immune functions can be reproduced inside its body
- Hematopoietic Stem Cell
- Hematopoietic stem cell: a cell that gives rise to the various types of blood cells. It can also keep producing copies of itself
- Undifferentiated
- Undifferentiated: the state in which a cell has not yet become a cell with a specific role
- Cooperative Graduate School Program
- Cooperative graduate school program: a system in which a university and a research institute sign an agreement so that students can earn a university degree while conducting research at the institute
NewsLab news
View More ↗ResearchResearch themes
In the hematopoietic system, the team uses humanized mice to study how a wide variety of blood and immune cells are produced from the most undifferentiated hematopoietic stem cells. Beyond the normal blood and immune system, the team aims to understand and overcome leukemia.
*Illustrative imageHow Blood and Immune Cells Are Made
The team follows how human immune cells derived from hematopoietic stem cells mature while moving among multiple organs of the body, aiming to understand how immune function arises.
*Illustrative imageLeukemia Relapse and Treatment
Leukemia can be regarded as tumor formation at an undifferentiated stage. By combining humanized mice with various research fields, the team investigates why leukemia relapses and what treatments can overcome relapse.
MembersFaculty
The members of the Human Disease Model Research Team consist of the team director, senior research scientists, special postdoctoral researchers, technical staff, and trainees.As of 2026
- Visiting ProfessorFumihiko Ishikawa
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Human Disease Model Lab
Immune Transcriptional Regulation LabGraduate School of Medicine, Cooperative ChairsConsidering that all somatic cells of a multicellular organi…
Mucosal System LabGraduate School of Medicine, Cooperative ChairsMucosal immunology: function and differentiation of intestin…
Immune Cell Therapy LabGraduate School of Medicine, Cooperative ChairsElucidation of immune activation and regulation in cancer an…
Medical Administration LabGraduate School of Medicine, Cooperative ChairsThe information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Sterile 24-Well Cell Culture Plate Used in Laboratory Research” Gannu03 / CC BY-SA 4.0 (cropped)
- How Blood and Immune Cells Are Made: “SEM blood cells” Bruce Wetzel (photographer). Harry Schaefer (photographer) / Public domain (cropped)
- Leukemia Relapse and Treatment: “Hairy cell leukemia smear” Paulo Henrique Orlandi Mourao / CC BY-SA 3.0 (cropped)
- Related lab (免疫転写制御研究チーム): “Laboratory of Molecular Biology” Jynto (talk) / Public domain (cropped)
- Related lab (粘膜システム研究チーム): “Immunology laboratory at the central cancer research labs” Unknown photographer / Public domain (cropped)
- Related lab (免疫細胞治療研究チーム): “Bioreactor for cell culture in the laboratory” Habin Zhang / CC BY-SA 4.0 (cropped)
- Related lab (医療行政学): “Mucosta (rebamipide) 100 mg tablets, Otsuka Pharmaceutical” 倶楽部オータム / CC BY-SA 3.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.