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クロマチン構造機能研究
Showing the original Japanese · View translation
クロマチンの構造を見て、遺伝子の働きの切り替わりを探る研究室。
AboutAbout the lab
クロマチンを見て、神秘のしくみを解く。
クロマチン構造機能研究室は、
DNAと
研究室の
胡桃坂教授は、
Key terms
- クロマチン
- DNAが
細胞核の 中に 収納されている形。 ヌクレオソームが 数珠状に 連なってできている - ヌクレオソーム
- 4種の
ヒストンタンパク質から なる 複合体の 周りに、 DNAが 巻き付いた 構造 - エピジェネティクス
- DNAの
塩基配列は 変わらないまま、 細胞ごとの 形や 働きの 違いを 生み出す 制御の メカニズム
NewsLab news
胡桃坂教授が、
武田科学振興財団の 2026年度 武田医学賞を 受賞 複合ヌクレオソーム上の
非対称な 転写の 構造基盤に ついて 論文を 発表 Rad26に
よる ヌクレオソームリモデリングの 構造基盤に ついて 論文を 発表 松本助教が、
2026年度日本生化学会奨励賞を 受賞 FACTと
協調する Set2の 転写共役H3K36トリメチル化の 構造基盤を 論文発表
ResearchResearch themes
同じ
*Illustrative image試験管でクロマチンを組み立てる
DNAと
*Illustrative image細胞からクロマチンを取り出す
細胞から
*Illustrative image細胞核内のクロマチンを直接見る
クライオ電子線トモグラフィー法で、
MembersFaculty
胡桃坂研究室の
- Professor胡桃坂 仁志
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Snf2 ATPase domain in complex with a nucleosome” EMBL-EBI / Public domain (cropped)
- 試験管で
クロマチンを 組み立てる : “Nucleosome at enhancer with H3K122 acetylated” MethylC5 / CC0 (cropped) - 細胞から
クロマチンを 取り出す: “Nucleus Nucleolus and chromatin of animal cell” Dan / CC BY-SA 3.0 (cropped) - 細胞核内の
クロマチンを 直接 見る : “Nucleus of cardiac fibroblasts” Lorenzo2697 / CC BY 4.0 (cropped) - Related lab (がんゲノム制御学): “Invasive Breast Cancer in 3D” Sshah74 / CC BY 4.0 (cropped)
- Related lab (アレルギー防御学): “Central-nervous-system” Another-anon-artist-234 / CC0 (cropped)
- Related lab (トランスクリプトミクス): “Chromatin Structures” Original uploader was Richard Wheeler at en.wikipedia / CC BY-SA 3.0 (cropped)
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