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Allergy Defense Lab
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A lab that explores how the brain and spinal cord work from an immunological perspective.
AboutAbout the lab
Exploring the central nervous system from an immunological perspective.
The Allergy Defense Lab studies immune functions that take place in the central nervous system, including the brain and spinal cord.
Its research keywords include central nervous system, immunity, cerebral infarction, γδ T cells, defense against infection, and IL-17A.
In recent papers, the lab has used mice to examine immune cells in the brain.
The lab belongs to the Division of Interdisciplinary Life Sciences at the Medical Institute of Bioregulation.
Key terms
- Central nervous system
- The group of nerves, made up of the brain and spinal cord, that serves as the center of the body's information processing
- γδ T cells
- A type of T cell, which is an immune cell. They are involved in defense against infection and other processes
- IL-17A
- A signaling molecule released by immune cells that is involved in inflammation
- Cerebral infarction
- A disease in which blood vessels in the brain become blocked, damaging brain tissue
ResearchResearch themes
This lab studies how immune cells function in the central nervous system. It is pursuing analyses focused on cerebral infarction and analyses of the functions of γδ T cells.
*Illustrative imageAnalysis of immune responses in the central nervous system
The lab analyzes how immune cells function in the central nervous system, including the brain and spinal cord. It has published a paper examining regulatory T cells in mouse models of cerebral infarction and multiple sclerosis.
*Illustrative imageFunctional analysis of γδ T cells
The lab investigates the functions of γδ T cells, focusing on defense against infection and IL-17A. It has published a paper reporting that, in a mouse model of autism spectrum disorder, γδ T cells accumulating in the brain reduce sociability.
MembersFaculty
- ProfessorMinako Ito
- Assistant ProfessorShinya Hatano
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Central-nervous-system” Another-anon-artist-234 / CC0 (cropped)
- Analysis of immune responses in the central nervous system: “Spinal cord gray matter immunofluorescence staining, confocal imaging” Wisstock / CC BY 4.0 (cropped)
- Functional analysis of γδ T cells: “Healthy Human T Cell” NIAID/NIH / Public domain (cropped)
- Related lab (Cancer Genome Regulation Lab): “Invasive Breast Cancer in 3D” Sshah74 / CC BY 4.0 (cropped)
- Related lab (Chromatin Structure and Function Lab): “Snf2 ATPase domain in complex with a nucleosome” EMBL-EBI / Public domain (cropped)
- Related lab (Stem Cell Medicine Lab): “Liquid nitrogen tank-13” real name: Matylda Sęk pl.wiki: Cygaretka commons: Cygaretka / CC BY-SA 3.0 (cropped)
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