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Green Pharma Division Lab
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A drug discovery research hub that integrates Eco-Pharma and green chemistry.
AboutAbout the lab
Integrating Eco-Pharma and green chemistry
The Green Pharma Division is one of the three divisions of the Green Pharma Institute, newly established to integrate and build on the achievements of the Green Chemistry Division and the Eco-Pharma Division.
The Faculty of Pharmaceutical Sciences has so far pursued ikuyaku research (Eco-Pharma), which extends approved drugs to new indications.
Combining this with green chemistry, which enables drug synthesis with low environmental impact, gives "Green Pharma," a research area that has developed as a distinctive strength of Kyushu University.
The institute works with the Green Pharma Structural Analysis Center, which performs structural and functional analysis using cryo-electron microscopy, and conducts drug discovery research based on the three-dimensional structures of molecules.
Key terms
- Eco-Pharma
- Ikuyaku research that extends approved drugs to new indications. It is a method of screening tens of thousands of existing drugs against target molecules.
- Green chemistry
- Chemistry that enables drug synthesis with low environmental impact.
- Cryo-electron microscope
- An electron microscope used to analyze the structure and function of molecules. It is used at the Green Pharma Structural Analysis Center.
- Clock genes
- A group of genes that drive circadian rhythms with a 24-hour cycle, such as the sleep-wake cycle and hormone secretion.
NewsLab news
View More ↗ResearchResearch themes
The Green Pharma Institute conducts "Green Pharma" drug discovery research that combines Eco-Pharma and green chemistry. In recent years it has also put effort into drug repositioning research, which extends the life cycle of drugs and creates new treatment options.
*Illustrative imageClock genes and drug efficacy
Prof. Koyanagi investigates, through rhythms of gene expression, how the effects and side effects of drugs change depending on the time of day they are taken. The professor also works on identifying new therapeutic target molecules from the relationship between clock genes and disease.
*Illustrative imageDrug development using the body clock
Prof. Matsunaga lists as research themes drug development based on the molecular mechanisms of the body clock (drugs for intractable breast cancer and anti-inflammatory drugs) and the development of technology that activates the body clock using microcurrent stimulation.
MembersFaculty
- ProfessorSatoru Koyanagi
- ProfessorNaoya Matsunaga
- ProfessorJose Caaveiro
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Medicinal plant , farm Research of KHORRAMAN Pharmaceutical co. - panoramio” Shahram Gandabi / CC BY 3.0 (cropped)
- Clock genes and drug efficacy: “Circadian clock of mammals” Nitramus / CC BY-SA 3.0 (cropped)
- Drug development using the body clock: “The Pharmaceutical Development Process” Bibeyjj / CC BY-SA 4.0 (cropped)
- Related lab (Green Chemistry Division Lab): “Pharmaceutical Chemistry Lab” 作者不詳 / Public domain (cropped)
- Related lab (Eco-Pharma Division Lab): “Active Transport - Protein Pumps” Christinelmiller / CC BY-SA 4.0 (cropped)
- Related lab (Environmentally Benign Medicinal Chemistry Lab): “Palladium on carbon” Marbletan / CC0 (cropped)
- Related lab (Physiology Lab): “Mitochondria 4 -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
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