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Internal Medicine Division, Brain and Neurological Diseases Research Institute Lab
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A lab that studies neuroimmune disorders and neuropathic pain from the perspective of neurology.
AboutAbout the lab
Exploring neuroimmune disorders through clinical practice and research
The Internal Medicine Division of the Brain and Neurological Diseases Research Institute is a lab that studies neurological diseases, mainly neuroimmune disorders.
Professor Isobe works as a neurologist, seeing patients in outpatient clinics and on hospital wards, while also pursuing neuroimmunological research, clinical epidemiological research, and genetic research.
Assistant Professor Fujii conducts research on neuropathic pain in neurology and supervises students in the doctoral program.
Key terms
- Neuropathic pain
- Pain caused by damage to the nerves themselves
- Neuromyelitis optica
- A neuroimmune disease in which inflammation occurs in the optic nerves and spinal cord
- Human leukocyte antigen
- Proteins on the cell surface that serve as markers by which the immune system recognizes cells. The type differs from person to person.
ResearchResearch themes
While working as neurologists treating patients, the lab studies neurological diseases, mainly neuroimmune disorders. In addition to research from the perspectives of neuroimmunology, clinical epidemiology, and genetics, it also studies neuropathic pain.
*Illustrative imageAnalysis of disease susceptibility genes
Focusing on multiple sclerosis and neuromyelitis optica, the lab is identifying genes involved in susceptibility to these diseases and examining how the genes relate to disease phenotypes. Human leukocyte antigen is also listed as a research theme.
*Illustrative imageResearch on neuropathic pain
From the standpoint of neurology, the lab studies neuropathic pain. It has worked on the development of new therapeutic drugs as a research theme.
MembersFaculty
- ProfessorNoriko Isobe
- Associate ProfessorRyo Yamasaki
- Assistant ProfessorTakayuki Fujii
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “MS Demyelinisation CD68 10xv2” Marvin 101 / CC BY-SA 3.0 (cropped)
- Analysis of disease susceptibility genes: “Human genetic diverging tree” Mayukh Mondal, Ferran Casals, Tina Xu, Giovanni M. Dall’Olio, Marc Pybus, Mihai G. Netea, David Comas, Hafid Laayouni, Qibin Li, Partha P. Majumder, Jaume Bertranpetit / CC BY-SA 4.0 (cropped)
- Research on neuropathic pain: “Pain-receptor neurons” NIH Image Gallery / Public domain (cropped)
- Related lab (Neuroanatomy Lab): “Sagittal brain slice, UB Museum of Neuroanatomy, Buffalo, New York” Caldwbr / CC BY-SA 4.0 (cropped)
- Related lab (Developmental and Regenerative Medicine Lab): “Mouse embryo ( )” Pazit Polak from Basel, Switzerland / CC BY 2.0 (cropped)
- Related lab (Medical Chemistry Lab): “DNA Structure+Key+Labelled.pn NoBB” Zephyris / CC BY-SA 3.0 (cropped)
- Related lab (Biochemistry Lab): “A Pathway to Protocells on Titan – Animations (SVS -Cell-Membrane-Thumbnail)” NASA's Scientific Visualization Studio - NASA Goddard / Public domain (cropped)
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