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Research Institute of Angiocardiology, Internal Medicine Lab
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An internal medicine lab that explores cardiovascular diseases such as heart failure and pulmonary hypertension through clinical practice and research.
AboutAbout the lab
Training physicians who combine clinical practice and research.
Kyushu University's cardiovascular medicine lab provides clinical care for heart failure, arrhythmia, ischemic heart disease, pulmonary hypertension, and congenital heart disease, and also conducts basic and clinical research.
Built on the foundation of the School of Medicine's Research Institute of Angiocardiology, it is made up of Cardiovascular Medicine in the Faculty of Medical Sciences and the Department of Cardiovascular Medicine at Kyushu University Hospital.
Its research groups are divided into clinical research on heart failure, arrhythmia, and related conditions, and basic research on heart failure, blood vessels, pulmonary hypertension, and hypertension.
The professor says the aim is to train physicians who combine advanced medical knowledge and skills with a mind for research.
Key terms
- CTEPH
- Chronic thromboembolic pulmonary hypertension. A disease in which blood clots left unresolved in the lungs cause pulmonary hypertension and right heart failure
- HFpEF
- Heart failure with preserved ejection fraction. It is said to be more common in older women
- Investigator-initiated clinical trial
- A clinical trial led by physicians to confirm the efficacy and safety of a drug
NewsLab news
A faculty member of the lab won the YIA Excellence Award and the Excellent Poster Award at the Basic Research Forum of the Japanese Circulation Society
The main paper of the QHEART-R study by Lecturer Hashimoto and colleagues was published in Circulation Journal
A paper examining changes in NT-proBNP levels and mortality risk in the Hisayama Study was published in Circulation Journal
A graduate student won an Excellence Award in the Medical Staff YIA at the Annual Scientific Meeting of the Japanese College of Cardiology
A paper on pulmonary arterial hypertension was published in the Journal of the American Heart Association
ResearchResearch themes
As a cardiovascular medicine lab, it pursues research on diseases such as heart failure and pulmonary hypertension, divided into clinical research and basic research groups. The main themes below are drawn from the faculty's researcher profiles.
*Illustrative imageBasic research on pulmonary hypertension and right heart failure
Right heart failure associated with pulmonary hypertension has a poor prognosis, so clarifying its pathology and developing new treatments are key challenges. Together with graduate students, the lab investigates how the obstructive lesions characteristic of pulmonary arterial hypertension progress and by what mechanism right heart failure worsens.
*Illustrative imageClinical research on chronic thromboembolic pulmonary hypertension
Professor Abe and colleagues built a nationwide multicenter registry for CTEPH, in which blood clots left unresolved in the lungs cause pulmonary hypertension and right heart failure. They also conducted a multicenter investigator-initiated clinical trial examining the efficacy and safety of direct oral anticoagulants.
*Illustrative imageBasic research on the pathology of heart failure
Lecturer Hashimoto continues basic research to clarify the pathology of HFpEF and right heart failure. In one study, a graduate student uses a rat model of hypertensive heart failure to examine the role of estrogen in acute exacerbation of HFpEF.
MembersFaculty
The lab's members consist of faculty, medical staff, and researchers; part-time staff; collaborative courses; and graduate and research students.
- ProfessorKotaro Abe
- Associate ProfessorShintaro Kinugawa
- Assistant ProfessorTakafumi Sakamoto
- LecturerToru Hashimoto
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Pulmonary Hypertension” BruceBlaus / CC BY-SA 4.0 (cropped)
- Basic research on pulmonary hypertension and right heart failure: “Birika arteriak eta zainak” Henry Vandyke Carter / CC0 (cropped)
- Clinical research on chronic thromboembolic pulmonary hypertension: “CTA Chest With Massive Pulmonary Embolism and Complete Occlusion” Rvahudson / CC BY-SA 4.0 (cropped)
- Basic research on the pathology of heart failure: “Cardiovascular system - Systolic heart failure -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
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