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Gastroenterology and Metabolism Lab
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A lab in gastroenterology and metabolism that studies whole-body metabolism starting from the gastrointestinal tract.
AboutAbout the lab
Creating a new research field at the boundary of gastroenterology and metabolism.
The Gastroenterology and Metabolism Lab studies the causes and pathophysiology of lifestyle-related diseases such as obesity and diabetes, focusing on connections between organs that start from the gastrointestinal tract.
The background is the finding that the gastrointestinal tract senses stimuli such as nutrients and produces hormones such as incretins, and that, together with the gut microbiota, it takes part in whole-body nutrient metabolism.
The lab combines basic research, multi-omics analysis (genome, epigenome, metabolome and others), and clinical research using the latest endoscopic equipment and endoscopic biopsy specimens, aiming to develop new diagnostic and treatment strategies.
As an affiliated lab of the Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, it also trains young researchers and physicians in the boundary area between gastroenterology and metabolism.
Key terms
- Incretin
- A hormone produced when the gastrointestinal tract senses nutrients. Examples include GLP-1 and GIP.
- Gut microbiota
- The community of bacteria living in the intestine.
- Multi-omics analysis
- Analysis that examines several types of molecular information together, such as the genome, epigenome and metabolome.
ResearchResearch themes
The lab investigates how inter-organ communication starting from the gastrointestinal tract regulates whole-body energy metabolism, aiming to clarify the causes and pathophysiology of lifestyle-related diseases such as obesity and diabetes. It combines basic and clinical research to develop new diagnostic and treatment strategies.
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MembersFaculty
- LecturerTakatoshi Chinen
- LecturerHaruei Ogino
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Lungs gall bladder liver stomach digestive tract-extract” See File:LA2-NSRW-2-0399.jpg / Public domain (cropped)
- Whole-body metabolism starting from the gastrointestinal tract: “Human Digestive Tract (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (Neuroanatomy Lab): “Sagittal brain slice, UB Museum of Neuroanatomy, Buffalo, New York” Caldwbr / CC BY-SA 4.0 (cropped)
- Related lab (Developmental and Regenerative Medicine Lab): “Mouse embryo ( )” Pazit Polak from Basel, Switzerland / CC BY 2.0 (cropped)
- Related lab (Medical Chemistry Lab): “DNA Structure+Key+Labelled.pn NoBB” Zephyris / CC BY-SA 3.0 (cropped)
- Related lab (Biochemistry Lab): “A Pathway to Protocells on Titan – Animations (SVS -Cell-Membrane-Thumbnail)” NASA's Scientific Visualization Studio - NASA Goddard / Public domain (cropped)
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