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Ocular Pathophysiology Imaging Lab
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A lab investigating eye diseases through immunology, imaging, and genomics.
AboutAbout the lab
Exploring eye diseases through immunology, imaging, and genomics
The lab studies eye diseases from the perspectives of immunology, imaging, and genomics.
For inflammatory eye diseases, alongside clinical care, it investigates why the diseases become prolonged and the diversity of NK cells.
It also works on deep learning using ophthalmic clinical images and on genomic analysis of cancers in the field of ophthalmology.
Genomic analysis of multifactorial diseases is another of its research themes.
Key terms
- NK cells
- A type of cell involved in immunity. The lab studies their diversity and immunological significance.
- Deep learning
- A method by which computers learn features from large amounts of data. This lab applies it to ophthalmic clinical images.
- Single-cell analysis
- An analytical method that separates cells and examines them one by one
ResearchResearch themes
The lab investigates the mechanisms of inflammatory eye diseases through immune diversity and cell analysis. It also conducts research using ophthalmic imaging and genomic data.
*Illustrative imageResearch on NK cell diversity
The lab investigates the diversity of KIR, HLA, and NK cells, and its immunological significance.
*Illustrative imageWhy eye inflammation becomes prolonged
The lab investigates the mechanisms and biomarkers behind prolonged inflammatory eye diseases. Host immunity and pathogen diversity involved in onset, and single-cell analysis, are also among its research themes.
*Illustrative imageDeep learning with ophthalmic images
The lab studies deep learning using ophthalmic clinical images.
*Illustrative imageGenomic analysis of ophthalmic cancers
The lab works on research analyzing cancer genomes in the field of ophthalmology.
MembersFaculty
- Associate ProfessorNobuyo Yawata
- Associate ProfessorMasato Akiyama
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “The Retina of My Eye” DavidBolnick / CC BY-SA 4.0 (cropped)
- Research on NK cell diversity: “Natural Killer Cell (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Why eye inflammation becomes prolonged: “Eye care for leprosy patient, India” The Leprosy Mission Ireland / CC BY 2.0 (cropped)
- Deep learning with ophthalmic images: “Fundus photograph of normal right eye” Mikael Häggström. When using this image in external works, it may be cited as: Häggström, Mikael (2014). "Medical gallery of Mikael Häggström 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.008. ISSN . Public Domain. or By Mikael Häggström, used with permission. / CC0 (cropped)
- Genomic analysis of ophthalmic cancers: “Cancer pharmacogenomics” Alejoaguia / CC BY-SA 4.0 (cropped)
- Related lab (Neuroanatomy Lab): “Sagittal brain slice, UB Museum of Neuroanatomy, Buffalo, New York” Caldwbr / CC BY-SA 4.0 (cropped)
- Related lab (Developmental and Regenerative Medicine Lab): “Mouse embryo ( )” Pazit Polak from Basel, Switzerland / CC BY 2.0 (cropped)
- Related lab (Medical Chemistry Lab): “DNA Structure+Key+Labelled.pn NoBB” Zephyris / CC BY-SA 3.0 (cropped)
- Related lab (Biochemistry Lab): “A Pathway to Protocells on Titan – Animations (SVS -Cell-Membrane-Thumbnail)” NASA's Scientific Visualization Studio - NASA Goddard / Public domain (cropped)
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