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Radiation Medical Information and Network Lab
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A lab studying high-precision radiotherapy for malignant tumors.
AboutAbout the lab
Exploring the usefulness and treatment strategies of high-precision radiotherapy
The lab studies radiotherapy for malignant tumors such as cancer.
It conducts research on stereotactic body radiotherapy and on radiotherapy strategies for brain metastases, and examines the usefulness of online adaptive radiotherapy for malignant tumors.
It also works on AI-based segmentation of pelvic lymph node regions and on photoimmunotherapy.
The lab is an endowed department in the Clinical Radiology field at the Faculty of Medical Sciences.
Key terms
- Online adaptive radiotherapy
- Radiotherapy in which the irradiation plan is re-created on the spot, based on the cone-beam CT images taken at each treatment session
- Radiosensitizer
- A drug that enhances the effect of radiotherapy. It is used together with radiation to achieve a synergistic effect.
- Drug repositioning
- A method of searching among safe, already-used drugs for one with a new action (here, enhancing the effect of radiation)
ResearchResearch themes
As an endowed department in Clinical Radiology, the lab studies high-precision radiotherapy for malignant tumors. In addition to verifying the usefulness of treatment methods and studying treatment strategies, it works on AI-based segmentation of pelvic lymph node regions, and has also searched for drugs that enhance the effect of radiation.
*Illustrative imageUsefulness of online adaptive radiotherapy
The lab verifies the usefulness of online adaptive radiotherapy for malignant tumors.
*Illustrative imageStereotactic body radiotherapy
The lab studies stereotactic body radiotherapy, one type of high-precision radiotherapy. It has also studied predicting recurrence after stereotactic body radiotherapy for non-small cell lung cancer by combining clinical factors with features of CT images (radiomics).
*Illustrative imageTreatment strategies for brain metastases and AI-based region segmentation
The lab studies radiotherapy strategies for brain metastases, and uses AI to segment pelvic lymph node regions.
Searching for drugs that enhance the effect of radiation
In esophageal squamous cell carcinoma, cancer stem cells resist radiation by suppressing reactive oxygen species. The lab studied drug repositioning, searching among drugs already in use for safe radiosensitizers with a strong synergistic effect.
MembersFaculty
- Associate ProfessorTadamasa Yoshitake
- Assistant ProfessorTomoko Shirakawa
- Assistant ProfessorHiroaki Wakiyama
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Varian-like Linear Accelerator for Precision Radiation Therapy” Bot1070 / CC0 (cropped)
- Usefulness of online adaptive radiotherapy: “Radiation therapy” Dina Wakulchik from Indianapolis, Indiana, USA / CC BY 2.0 (cropped)
- Stereotactic body radiotherapy: “Robotic CyberKnife at St. Marys Of Michigan” Communications Manager / CC BY 2.0 (cropped)
- Treatment strategies for brain metastases and AI-based region segmentation: “Brain MRI 0145 02” Nevit Dilmen (talk) / CC BY-SA 3.0 (cropped)
- Related lab (Neuroanatomy Lab): “Sagittal brain slice, UB Museum of Neuroanatomy, Buffalo, New York” Caldwbr / CC BY-SA 4.0 (cropped)
- Related lab (Developmental and Regenerative Medicine Lab): “Mouse embryo ( )” Pazit Polak from Basel, Switzerland / CC BY 2.0 (cropped)
- Related lab (Medical Chemistry Lab): “DNA Structure+Key+Labelled.pn NoBB” Zephyris / CC BY-SA 3.0 (cropped)
- Related lab (Biochemistry Lab): “A Pathway to Protocells on Titan – Animations (SVS -Cell-Membrane-Thumbnail)” NASA's Scientific Visualization Studio - NASA Goddard / Public domain (cropped)
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