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Perinatal and Pediatric Medicine Obstetrics Lab
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An obstetrics lab that uses basic research to study the cells of endometrial cancer and the placenta.
AboutAbout the lab
Exploring the cellular mechanisms of the uterus and placenta
The Perinatal and Pediatric Medicine Obstetrics Lab uses basic research to study how endometrial cancer develops and how trophoblast cells, which form the placenta, differentiate.
Aging and inflammation of the endometrium are also among its research themes.
Key terms
- Endometrial cancer (uterine corpus cancer)
- Cancer that develops in the membrane lining the inside of the uterus (the endometrium). Also called endometrial carcinoma.
- Trophoblast cells
- Cells that form the placenta
- Epithelial-mesenchymal transition
- A change in which the connections between cells loosen and the cells acquire the ability to move around. It is involved in the invasion of cancer cells.
ResearchResearch themes
The lab uses basic research to study how endometrial cancer develops and how trophoblast cells, which form the placenta, differentiate. It also studies aging and inflammation of the endometrium.
*Illustrative imageMechanisms of malignant transformation in endometrial cancer
The lab uses basic research to study how endometrial cancer develops. It also examines the process in which cells undergo epithelial-mesenchymal transition and invade surrounding tissue, as well as the regulation of metabolism involved in it.
*Illustrative imageDifferentiation of placental trophoblast cells
The lab uses basic research to study how trophoblast cells of mice, rats, and humans differentiate.
*Illustrative imageAging and inflammation of the endometrium
The lab studies aging and inflammation of the endometrium.
MembersFaculty
- Associate ProfessorKazuo Asanoma
- Assistant ProfessorKeiko Kawamura
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Microscope - school laboratory (2)” Kvr.lohith / CC BY-SA 4.0 (cropped)
- Mechanisms of malignant transformation in endometrial cancer: “Histopathology of endometrial cancer with lymphovascular invasion” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). / CC0 (cropped)
- Differentiation of placental trophoblast cells: “Histopathology of chorionic villi at gestational age of 9 weeks” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). / CC0 (cropped)
- Aging and inflammation of the endometrium: “Secretory phase endometrium” No machine-readable author provided. KGH assumed (based on copyright claims). / CC BY-SA 3.0 (cropped)
- Related lab (Neuroanatomy Lab): “Sagittal brain slice, UB Museum of Neuroanatomy, Buffalo, New York” Caldwbr / CC BY-SA 4.0 (cropped)
- Related lab (Developmental and Regenerative Medicine Lab): “Mouse embryo ( )” Pazit Polak from Basel, Switzerland / CC BY 2.0 (cropped)
- Related lab (Medical Chemistry Lab): “DNA Structure+Key+Labelled.pn NoBB” Zephyris / CC BY-SA 3.0 (cropped)
- Related lab (Biochemistry Lab): “A Pathway to Protocells on Titan – Animations (SVS -Cell-Membrane-Thumbnail)” NASA's Scientific Visualization Studio - NASA Goddard / Public domain (cropped)
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