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Dermatology Lab
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The lab investigates atopic dermatitis, itch, and malignant skin tumors through both basic and clinical research.
AboutAbout the lab
Pursuing progressive growth with diversity as its motto.
The Dermatology Lab studies atopic dermatitis, itch, malignant skin tumors, and related conditions.
Aiming to clarify disease mechanisms and lead to the development of new treatments, the lab carries out both basic and clinical research.
The lab also studies the signaling pathway of AHR (aryl hydrocarbon receptor), which acts as a sensor for chemical substances.
With diversity as its motto, the lab aims to be a strong organization that keeps adapting to changing times and pursues progressive growth, and one that is kind to its people.
Key terms
- AHR
- Aryl hydrocarbon receptor. It acts as a sensor for chemical substances and is highly expressed in the skin.
- Malignant skin tumors
- Malignant tumors that arise in the skin. They include melanoma, squamous cell carcinoma, and angiosarcoma.
ResearchResearch themes
Among skin diseases, the lab focuses mainly on atopic dermatitis, itch, and malignant skin tumors, aiming to clarify disease mechanisms and develop new treatments. In addition to basic and clinical research using patient samples, questionnaires, and mouse models, the lab also studies AHR, a sensor for chemical substances.
*Illustrative imageBasic research on the pathology of atopic dermatitis
Aiming to contribute to clarifying disease mechanisms and developing new treatments, the lab conducts broad research on topics such as the relationship of cytokines, mediators, and intracellular signaling to inflammation and itch, the role of dendritic cells, and epidermal barrier function.
*Illustrative imageClinical research on atopic dermatitis
The lab examines the usefulness of questionnaires that capture symptoms and the burden on daily life, and analyzes the disease in childhood and adulthood using samples of the stratum corneum and skin lipids. It seeks to uncover important facts that cannot be obtained from experiments in the lab.
*Illustrative imageResearch on the mechanisms of itch
Itch is one of the main symptoms of skin diseases, yet much remains unknown about its pathology and how it arises. To clarify this, the lab conducts questionnaire surveys of patients with itch and studies regulatory mechanisms using mouse models.
*Illustrative imagePathology and treatment of malignant skin tumors
Using clinical samples and cell lines of malignant skin tumors such as melanoma, the lab aims to clarify disease mechanisms and develop new treatments. It focuses on epithelial-mesenchymal transition, cancer stem cells, single-cell analysis, antibody-drug conjugates, and tumor heterogeneity.
MembersFaculty
The members of the Dermatology Lab consist of Professors, Associate Professors, Lecturers, Assistant Professors, clinical staff physicians, Kirameki Project staff, and staff who are away on assignment.As of 2026
- ProfessorTakeshi Nakahara
- Associate ProfessorManabu Tsuji
- LecturerYoko Fuyuno
- LecturerKazuhiko Yamamura
- LecturerFumitaka Ono
- Assistant ProfessorNobuhajime Take
- Assistant ProfessorToshio Ichiki
- Assistant ProfessorKeiichi Inoue
- Assistant ProfessorYuka Tanaka
- Assistant ProfessorAyako Yumine
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Morpheus- Skin Rejuvenation by Dr.Marwah” Drsiddharthsen / CC0 (cropped)
- Basic research on the pathology of atopic dermatitis: “Atopic dermatitis child” The original uploader was Eisfelder at German Wikipedia. / CC BY-SA 3.0 (cropped)
- Clinical research on atopic dermatitis: “Chronic eczema new photo for helping in diagnosis” Masryyy / CC BY-SA 4.0 (cropped)
- Research on the mechanisms of itch: “Bear Scratching Itch ( )” KatmaiNPS / Public domain (cropped)
- Pathology and treatment of malignant skin tumors: “Melanoma in situ Right Forehead dermatoscope” Dermanonymous / CC BY-SA 4.0 (cropped)
- Related lab (Growth and Developmental Medicine Lab): “Itzhak Levy 2” דוברות מרכז שניידר לרפואת ילדים בישראל / CC BY-SA 4.0 (cropped)
- Related lab (Urology Lab): “Ultrasound of left kidney lower pole with stone” Cerevisae / CC BY-SA 4.0 (cropped)
- Related lab (Structural Pathology Lab): “Histology of liver tissue from a gallbladder resection” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). / CC0 (cropped)
- Related lab (Biochemistry Lab): “A Pathway to Protocells on Titan – Animations (SVS -Cell-Membrane-Thumbnail)” NASA's Scientific Visualization Studio - NASA Goddard / Public domain (cropped)
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