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Urology Lab
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A urology lab that studies cancers of the kidney and urinary tract from both clinical and basic research angles.

AboutAbout the lab
Answering clinical questions through basic research
The Urology Lab pursues research while making the diagnosis and treatment of malignant tumors of the kidney, adrenal gland, urinary tract, and male reproductive organs the core of its clinical practice.
In its research, the lab works to clarify questions that arise in the clinic through basic research and to connect the findings to the development of new treatments.
The lab also studies the behavior of immune cells around tumors using patient samples, and searches for biomarkers that can be measured in urine and blood.
In education, the lab focuses on clinical clerkships for undergraduates, and for graduate students it promotes collaboration with basic medicine departments and study abroad.
Key terms
- Immune checkpoint inhibitors
- Drugs used in systemic cancer therapy, typified by PD-1 pathway inhibitors.
- Biomarker
- An indicator measurable from the body that can lead to early detection of cancer or assessment of prognosis.
- Castration-resistant prostate cancer
- Prostate cancer that keeps progressing even when treatment that suppresses male hormones is continued.
NewsLab news
A staff physician won the Excellent Presentation Award at the Fukuoka Regional Meeting of the Japanese Urological Association.
An Assistant Professor won the Best Presentation Award at the 56th Kidney Cancer Research Meeting.
An Assistant Professor's paper was accepted by European Journal of Nuclear Medicine and Molecular Imaging Research.
An Assistant Professor won the Excellent Presentation Award at the 6th JOHBOC Annual Meeting.
A Lecturer's paper was published in World Journal of Urology.
ResearchResearch themes
The lab aims to clarify questions that arise in the clinic through basic research and to lead to the development of new treatments. It studies the building and application of multidisciplinary cancer treatment models, the behavior of immune cells at the local tumor site, and biomarkers using urine and blood.
*Illustrative imageCancer Treatment Models, Immunity, and Biomarkers
The lab is working on building cancer treatment models that combine therapies, including immune checkpoint inhibitors, and on applying them. Using patient samples, it examines the behavior of immune cells around tumors, and it also conducts research on biomarkers using urine and blood.
*Illustrative imageProstate and Bladder Cancer and the Androgen Receptor
Associate Professor Shiota's research themes are the androgen receptor in prostate and bladder cancer, the mechanisms by which castration-resistant prostate cancer arises, and clinical studies of the mechanisms by which prostate cancer progresses.
MembersFaculty
The lab's members consist of a Professor, Associate Professor, Lecturer, Assistant Professor, and staff physicians.As of 2026
- ProfessorMasatoshi Eto
- Associate ProfessorMasaki Shiota
- Lecturer, Clinical Associate ProfessorTakashi Matsumoto
- LecturerSatoshi Kobayashi
- Assistant Professor, Clinical LecturerTokiyoshi Tanegashima
- Assistant ProfessorShigehiro Tsukahara
- Assistant ProfessorShohei Nagakawa
- Assistant ProfessorDai Takamatsu
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Ultrasound of left kidney lower pole with stone” Cerevisae / CC BY-SA 4.0 (cropped)
- Cancer Treatment Models, Immunity, and Biomarkers: “T Regulatory Cells ( )” NIAID / CC BY 2.0 (cropped)
- Prostate and Bladder Cancer and the Androgen Receptor: “Prostate Cancer ( )” National Human Genome Research Institute (NHGRI) from Bethesda, MD, USA / CC BY 2.0 (cropped)
- Related lab (Pathophysiology and Restorative Internal Medicine Lab): “SEM blood cells” Bruce Wetzel (photographer). Harry Schaefer (photographer) / Public domain (cropped)
- Related lab (Ophthalmology Lab): “Eye Exam - Eye Doctor ( )” Tony Webster / CC BY 2.0 (cropped)
- Related lab (Morphology and Functional Pathology Lab): “Smooth muscle (histology slide)” Juan Carlos Fonseca Mata / CC BY-SA 4.0 (cropped)
- Related lab (Structural Pathology Lab): “Histology of liver tissue from a gallbladder resection” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). / CC0 (cropped)
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