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Collaborative Oncology Lab
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A lab that works to uncover the mechanisms of cancer immunity and carcinogenesis.

AboutAbout the lab
Opening new possibilities for overcoming cancer through knowledge and research.
The Collaborative Oncology field conducts research toward the prevention, diagnosis, and treatment of cancer, and is engaged in cancer education, as part of the Department of Social and Environmental Medicine in the Faculty of Medical Sciences.
It was established in April 2024 through the merger of the Collaborative Social Medicine field and the Basic Radiation Medicine field.
In medical school education, the lab offers opportunities to learn the molecular biology of cancer and cancer genomic medicine through lectures on medical oncology and genetics.
The lab is strengthening its collaboration with the Cancer Center of Kyushu University Hospital and is advancing research on cancer immunity, mechanisms of carcinogenesis, drug resistance, and related topics.
Key terms
- Immune checkpoint inhibitors
- Cancer immunotherapy drugs that target the mechanisms by which cancer cells escape immune surveillance
- Mutation
- A change in genetic information. When it occurs in somatic cells, it can cause cancer and aging
- DNA repair
- The cellular mechanisms that restore damaged DNA
NewsLab news
Paper by Assistant Professor Hirofumi Ohmura published in International Journal of Clinical Oncology
Paper by Prof. Baba and colleagues published in Japanese Journal of Clinical Oncology
Prof. Eishi Baba received the Special Award for Industry-Academia-Government Collaboration Activities
Paper by Prof. Baba and colleagues published in International Cancer Conference Journal
Paper by Prof. Baba and colleagues published in ESMO Open
ResearchResearch themes
The lab conducts research on the prevention, diagnosis, and treatment of cancer. Centered on the role of immunity against cancer, the mechanisms by which cancer arises, the prediction of treatment response, and the occurrence and suppression of mutations, it aims to overcome cancer.
*Illustrative imageUnderstanding the cancer immune response
The response rate to immune checkpoint inhibitors is limited in many types of cancer. The lab analyzes the characteristics and dynamics of immune cells, including at the single-cell level and with spatial information, with the aim of clarifying the mechanisms of treatment resistance.
*Illustrative imageMechanisms of colorectal cancer development and novel therapies
From the perspectives of cancer-initiating (stem) cells, epigenetic abnormalities, chromosomal abnormalities, clonal hematopoiesis, and senescent cells, the lab analyzes the mechanisms of colorectal cancer development and progression at the molecular level, with the aim of developing new therapies.
*Illustrative imagePredicting the effect of immune checkpoint inhibitors
Using blood and tissue samples from treated patients, the lab examines the immune cell subsets and cytokines associated with treatment response and resistance. The lab hopes to find predictive factors for treatment effect and contribute to establishing more precise cancer immunotherapy.
*Illustrative imageMechanisms of mutation occurrence and suppression
Using knockout mice for genes involved in DNA repair, the lab investigates how DNA damage leads to mutations and cancer, and how damage occurring in germ cells affects the genomes of offspring.
MembersFaculty
The members of the Collaborative Oncology Lab consist of faculty members, joint researchers, and collaborating researchers.As of 2026
- ProfessorEishi Baba
- Assistant ProfessorHirofumi Ohmura
- Assistant ProfessorTomoyasu Yoshihiro
- Assistant ProfessorMizuki Ohno
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Killer T cells surround a cancer cell” The National Institutes of Health / Public domain (cropped)
- Understanding the cancer immune response: “Effect of immune cells on Tumors” ThatBio / CC0 (cropped)
- Mechanisms of colorectal cancer development and novel therapies: “Blausen 0246 ColorectalCancer” Blausen Medical Communications, Inc. / CC BY 3.0 (cropped)
- Predicting the effect of immune checkpoint inhibitors: “PD-1, PD-L1 and CTLA-4 targets of immune checkpoint inhibitors” Alexandre Perrier, Audrey Didelot, Pierre Laurent-Puig, Hélène Blons and Simon Garinet / CC BY 4.0 (cropped)
- Mechanisms of mutation occurrence and suppression: “DNA Repair” Tom Ellenberger, Washington University School of Medicine in St. Louis. / Public domain (cropped)
- Related lab (Morphology and Functional Pathology Lab): “Smooth muscle (histology slide)” Juan Carlos Fonseca Mata / CC BY-SA 4.0 (cropped)
- Related lab (Pathophysiology and Restorative Internal Medicine Lab): “SEM blood cells” Bruce Wetzel (photographer). Harry Schaefer (photographer) / Public domain (cropped)
- Related lab (Pharmacology Lab): “Фармацевтско-лабараториски техничар” Blagojcedisoski / CC BY-SA 3.0 (cropped)
- Related lab (Urology Lab): “Ultrasound of left kidney lower pole with stone” Cerevisae / CC BY-SA 4.0 (cropped)
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