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Microbial Technology Lab
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The lab studies the human gut microbiota and the antibacterial peptides produced by lactic acid bacteria.
AboutAbout the lab
Global gut microbiology that contributes to healthy longevity for humankind.
The Microbial Technology Lab studies the gut microbiota of people around the world, aiming to understand the relationship between diet and health.
The lab analyzes the gut microbiota through joint research with microbiologists, medical researchers, and researchers in industry around the world.
The lab also studies the mechanism of toxin production by pathogenic bacteria in the gut (quorum sensing) and how to control it.
In addition, the lab studies the structure, function, biosynthesis mechanism, and applications of bacteriocins, antibacterial peptides produced by lactic acid bacteria.
Key terms
- Gut microbiota
- A microbial community made up of the many bacteria that live symbiotically in the human intestine. Also called gut flora.
- Bacteriocin
- An antibacterial peptide produced by lactic acid bacteria. It is expected to be used in a variety of applications as a highly safe antibacterial substance.
- Quorum sensing
- A mechanism in which microorganisms signal their population density to one another through secreted substances and collectively switch the expression of specific genes.
ResearchResearch themes
The lab aims to understand the relationship between diet and health by studying the gut microbiota of people around the world, and thereby to contribute to healthy longevity for humankind. It also studies the structure, function, biosynthesis mechanism, and applications of bacteriocins, antibacterial peptides produced by lactic acid bacteria.
*Illustrative imageGut microbiota and diet of people around the world
The lab analyzes the gut microbiota of people around the world to understand the relationship between diet and health. It aims to share knowledge about diets that help maintain a beneficial gut microbiota.
*Illustrative imageQuorum sensing in pathogenic gut bacteria
The lab has aimed to develop drugs that block quorum sensing so that bacteria can still grow but stop producing toxins. In recent years, it has also focused on quorum sensing in the gut microbiota.
*Illustrative imageBacteriocins of lactic acid bacteria
Antibacterial peptides produced by lactic acid bacteria, which are widely found in fermented foods and elsewhere, are expected to be used in a variety of applications as highly safe antibacterial substances. The lab searches for bacteriocins with excellent properties and studies their structure and function, biosynthesis mechanism, and applications.
MembersFaculty
The members of the Microbial Technology Lab include faculty, doctoral, master's, and undergraduate students, and special research students.
- ProfessorJiro Nakayama
- Associate ProfessorTakeshi Zendo
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Joghurt” No machine-readable author provided. Rainer Zenz assumed (based on copyright claims). / CC BY-SA 3.0 (cropped)
- Gut microbiota and diet of people around the world: “Making soy sauce (fermentation)” Pauloleong2002 / CC BY-SA 4.0 (cropped)
- Quorum sensing in pathogenic gut bacteria: “Bacteria in the gut” NIH Image Gallery / CC BY 2.0 (cropped)
- Bacteriocins of lactic acid bacteria: “Yogurt made from EM rice wash” Zenyrgarden / CC BY-SA 4.0 (cropped)
- Related lab (Microbial Genetic Resources Lab): “Aerial image of Grand Prismatic Spring (view from the south)” Carsten Steger / CC BY-SA 4.0 (cropped)
- Related lab (Marine Resource Chemistry Lab): “Seawater and rocks” Deishini Mariam / CC BY-SA 4.0 (cropped)
- Related lab (Food Hygiene Chemistry Lab): “LUA, Faculty of Food Technology Food microbiology laboratory” Turaids / CC BY-SA 4.0 (cropped)
- Related lab (Biophysical Chemistry Lab): “Crystal structure ( )” Jun from Melbourne, Australia / CC BY-SA 2.0 (cropped)
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