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Fermentation Chemistry Lab
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The lab elucidates the functions of yeasts and filamentous fungi to develop microorganisms with advanced capabilities.
AboutAbout the lab
Unraveling the diverse functions of microorganisms at the molecular level
The Fermentation Chemistry Lab studies eukaryotic microorganisms, mainly yeasts and filamentous fungi, and elucidates their diverse functions at the molecular level.
Using genetic engineering, protein engineering, and cell biology, the lab gives microorganisms new functions or enhances their existing ones.
The lab also conducts basic research that searches for and isolates new useful microorganisms from nature, with the aim of putting them to effective use.
The lab's website introduces it under the name "Fermentation Chemistry Laboratory."
Key terms
- Filamentous fungi
- Microorganisms that grow by extending thread-like cells called hyphae
- Glycan
- A chain-like molecule made of many sugars linked together, often attached to proteins and other molecules
- Endoglycosidase
- A type of enzyme that cleaves glycans attached to glycoproteins
ResearchResearch themes
The Fermentation Chemistry Lab focuses on yeasts and filamentous fungi, which are eukaryotic microorganisms, and elucidates their diverse functions at the molecular level. Using genetic engineering, protein engineering, and cell biology, the lab adds new functions and analyzes and enhances existing ones, working to develop microorganisms with advanced capabilities.
*Illustrative imageAnalysis of intracellular vesicular transport in yeast
The lab studies the pathways that transport substances by means of vesicles inside yeast cells. Applications of this transport are also a subject of the research.
*Illustrative imageGalactofuranose-containing glycans of filamentous fungi
The lab studies the enzymes involved in the synthesis and degradation of glycans produced by filamentous fungi that contain a sugar called galactofuranose.
*Illustrative imageModifying and analyzing glycans of biopharmaceuticals
The lab develops technologies to modify and analyze the glycans of glycoproteins used as biopharmaceuticals, using endoglycosidases, which are enzymes found in microorganisms.
*Illustrative imageGlycan synthesis in fission yeast and its roles
The lab studies how galactose-containing glycans are synthesized in fission yeast. It also aims to clarify what roles pyruvylated glycans play.
MembersFaculty
The members of the Fermentation Chemistry Lab consist of faculty members, cooperating faculty members, technical specialists, technical assistants, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorKaoru Takegawa
- Associate ProfessorYujiro Higuchi
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Yeast cells in Gram stain” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Analysis of intracellular vesicular transport in yeast: “Yeast Cells in Wet Mount Microscopy of Culture” Ajay Kumar Chaurasiya / CC0 (cropped)
- Galactofuranose-containing glycans of filamentous fungi: “Aspergillus flavus” Medmyco / CC BY-SA 4.0 (cropped)
- Modifying and analyzing glycans of biopharmaceuticals: “BTEC Bioreactors” RickLawless (talk) (Uploads) / CC BY 3.0 (cropped)
- Glycan synthesis in fission yeast and its roles: “Fission yeast division” G Lens Microscopist, Liam Pennington / CC BY 4.0 (cropped)
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- Related lab (Mathematical Modeling Lab): “Top supercomputers at universities in the United States” Wikideas1 / CC0 (cropped)
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