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Quantitative Immunology Lab
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The lab reconstructs the gene regulatory networks of immune cells using single-cell data and computation.

AboutAbout the lab
Solving immunology quantitatively through computation and measurement.
The Quantitative Immunology Research Unit is a research group where researchers from different fields come together, aiming to advance the understanding of immunology through interdisciplinary research.
Its work rests on three pillars: quantitative single-cell measurement, integration of omics data, and mathematical modeling of the immune system.
The lab combines computational methods with single-cell gene expression data to reconstruct the gene regulatory networks that determine the identity and function of immune cells.
The lab belongs to an interdisciplinary research unit at the Immunology Frontier Research Center (IFReC), and the lab's website is written in English.
Key terms
- Gene regulatory network
- A web-like structure formed when regulators such as transcription factors control the expression of many genes, and some of those genes in turn become regulators
- Omics data
- Data that comprehensively measure the molecules inside cells, such as gene expression
- Transcription factor
- One type of regulator that controls gene expression. Others include chromatin modifiers
ResearchResearch themes
The identity and function of immune cells are determined in part by their gene expression patterns. Through quantitative single-cell measurement, integration of omics data, and mathematical modeling, the lab aims to understand the immune system across disciplines.
View More ↗MembersFaculty
- Associate ProfessorDiego Diez
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Gene Regulatory Network 2” 作者不詳 / Public domain (cropped)
- Reconstructing gene regulatory networks in the immune system: “Gene Regulatory Network” 作者不詳 / Public domain (cropped)
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