LAB LOGA page on LabLog, a review site (not the lab's official page)
Immune Regulation Lab
Machine-translated · View original
A lab that explores the mechanisms of autoimmune disease through the cytokine IL-6.
AboutAbout the lab
IL-6 research, from bench to bedside
The Immune Regulation Lab, part of the Immunology Group at the Immunology Frontier Research Center (IFReC), studies how autoimmune diseases arise and the cytokine signaling pathways involved.
The discovery of interleukin-6 (IL-6) and the elucidation of its receptor signaling pathway revealed that cytokines play an important role in regulating immune cells.
When cytokine regulation is disrupted, immune cells can be activated inappropriately, which can lead to autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus.
The lab aims to deepen the understanding of autoimmune diseases and cytokine signaling pathways, and ultimately to contribute to better medical care.
Key terms
- Cytokine
- A substance that regulates the activity of immune cells. When its regulation is disrupted, immune cells are activated inappropriately.
- Th17 cells
- Helper T cells that produce interleukin-17 (IL-17). They are involved in autoimmune diseases such as multiple sclerosis.
- Autoimmune disease
- Diseases such as rheumatoid arthritis and systemic lupus erythematosus. Disrupted cytokine regulation can be one step in their onset.
ResearchResearch themes
The discovery of IL-6 and the elucidation of its receptor signaling pathway showed the important role cytokines play in regulating immune cells. The lab aims to understand the mechanisms of autoimmune diseases and the cytokine signaling pathways involved, and to apply that understanding to improving medical care.
*Illustrative imageIL-6 and Treg/Th17 cell differentiation
The lab works to elucidate how IL-6 controls the differentiation of Treg and Th17 cells, and uses anti-IL-6 receptor antibody as a tool to clarify how intractable immune diseases develop.
*Illustrative imageInteractions between vascular cells and immune cells
The lab works to elucidate how immune responses are controlled through interactions between vascular cells and immune cells.
MembersFaculty
- Project ProfessorTadamitsu Kishimoto
- Associate ProfessorKang Sujin
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Immune Regulation Lab
Host Defense LabImmunology Frontier Research Center, Immunology GroupPattern recognition receptors and signaling factors; regulat…
Immunochemistry LabImmunology Frontier Research Center, Immunology GroupPeptide antigen presentation by MHC; disease gene functions …
Mucosal Immunology LabImmunology Frontier Research Center, Immunology GroupEtiology and pathogenesis of inflammatory bowel disease; mai…
Experimental Immunology LabImmunology Frontier Research Center, Immunology GroupMechanisms of maintaining immunological self-tolerance by re…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Rheumatoid arthritis with unaffected carpal bones 2009” Mikael Häggström / CC0 (cropped)
- IL-6 and Treg/Th17 cell differentiation: “HIV-infected T cell ( )” NIAID / CC BY 2.0 (cropped)
- Interactions between vascular cells and immune cells: “Interaction between Kupffer cells, Stellate cells and endothelial cells” Bonnardel Johnny / CC BY-SA 4.0 (cropped)
- Related lab (Host Defense Lab): “Peritoneal fluid sediment in Wright Staining” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (Immunochemistry Lab): “Westgate Microscopy t-lymphocytes” Cannons Law Firm, Glasgow, UK / CC BY 4.0 (cropped)
- Related lab (Mucosal Immunology Lab): “Culture Plates” Katherine Stember / CC BY 4.0 (cropped)
- Related lab (Experimental Immunology Lab): “HIV H9 T-cell II” National Institutes of Health (NIH) / Public domain (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.