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Kamimoto Lab
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The lab decodes and predicts the regulatory rules of life in silico.
AboutAbout the lab
Advancing biology, medicine, and bioengineering research through interdisciplinary integration
The Kamimoto Lab reconstructs in silico the regulatory circuits of living systems that cells and genes form, drawing on large and complex datasets.
From models of life built in silico, the lab aims to decipher the complex rules of biological regulation and to use them for predictive simulation as well.
The lab conducts both biological experiments using cultured cells (wet research) and data analysis using AI and machine learning (dry research).
It focuses in particular on cancer, aging, stem cell differentiation, and gene regulation and the epigenome.
Key terms
- in silico
- An approach to studying the mechanisms of life using models of living systems reconstructed on a computer
- Wet research
- Research based on biological experiments such as cultured cell experiments and DNA experiments
- Dry research
- Research based on data analysis such as AI, machine learning, bioinformatics, and modeling
NewsLab news
View More ↗ResearchResearch themes
The lab aims to elucidate how cells and tissues are formed and maintained, and to manipulate cells based on that understanding. Using new measurement technologies together with AI, machine learning, and bioinformatics, it decodes the rules of life from data, then builds and applies predictive models.
*Illustrative imageDecoding the rules of life from data
Combining new measurement technologies with AI, machine learning, and bioinformatics, the lab interprets biological data. It aims to decode and understand complex rules of life that exist beyond the limits of human cognition.
*Illustrative imageModels that predict the behavior of living systems
From the decoded data, the lab builds computational models that predict and reproduce the behavior of living systems. These predictive models are applied in life science and medical research.
*Illustrative imageDesigning and manipulating cells and tissues with models
Using predictive models, the lab develops technologies to rationally design and manipulate cells and tissues. It conducts bioengineering research that does not depend on random discovery, and develops treatments for diseases.
MembersFaculty
- ProfessorKenji Kamimoto
- Assistant ProfessorKenji Ito
- Project Assistant ProfessorShuhei Nozaki
- Project Assistant ProfessorYuki Hagiwara
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Beckman Coulter CEQ 8800” Herodotptlomeu / CC BY-SA 4.0 (cropped)
- Decoding the rules of life from data: “TIGR lab Old DNA sequencers” Steve Jurvetson / CC BY 2.0 (cropped)
- Models that predict the behavior of living systems: “Athena supercomputer cluster” NASA / Public domain (cropped)
- Designing and manipulating cells and tissues with models: “Synthetic Biology Research at NASA Ames” Alexander van Dijk from San Francisco, United States / CC BY 2.0 (cropped)
- Related lab (情報伝達分野 高倉研究室): “Bovine Pulmonary Artery Endothelial Cells Fluorescent Image 3” Erin Rod / CC BY 4.0 (cropped)
- Related lab (感染腫瘍制御分野 幸谷研究室): “Epstein-Barr Virus (EBV) Particles” NIAID / CC BY 2.0 (cropped)
- Related lab (ウイルス免疫分野 小林研究室): “Multiple rotavirus particles” Dr Graham Beards / CC BY 3.0 (cropped)
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