LAB LOGA page on LabLog, a review site (not the lab's official page)
Hara Lab
Machine-translated · View original
The lab explores the link between aging and cancer through the mechanisms of cellular senescence.
AboutAbout the lab
Exploring where aging and cancer meet.
The Hara Lab, in the Division of Molecular Biology, studies the relationship between aging and cancer, focusing on the phenomenon of cellular senescence.
Cellular senescence is one of the safeguards by which cells stop proliferating when they detect abnormalities, and it acts to suppress cancer.
On the other hand, the lab considers that senescent cells accumulating in the body with aging and obesity are one cause of the onset of various inflammatory diseases, including cancer.
The lab aims to clarify how cellular senescence occurs and what it does, and to develop methods to control it.
Key terms
- Cellular senescence
- One of the safeguards by which cells stop proliferating when they detect abnormalities. It acts to suppress the development of cancer.
- Senescent cells
- Cells that have undergone cellular senescence. They are thought to accumulate in the body with aging and obesity.
- SASP
- A phenomenon in which senescent cells highly express various secreted factors, such as inflammatory cytokines and growth factors.
NewsLab news
Paper on problems in detecting and eliminating senescent cells in p16-3MR mice published in EMBO Reports
Paper re-examining the effects of senolytic drugs published in EMBO Reports
ResearchResearch themes
Cellular senescence is a safeguard that suppresses cancer, but it is becoming clear that senescent cells also have a side effect: through a phenomenon called SASP, in which they secrete various substances, they cause inflammation and promote carcinogenesis. The lab aims to clarify the mechanisms by which cellular senescence is induced and its role in the living body, and to develop methods to control cellular senescence.
How senescent cells increase
The lab aims to clarify the mechanisms by which senescent cells increase in the body with aging, and to explore ways to control that increase.
*Illustrative imageCellular senescence and COVID-19
The lab aims to clarify the relationship between cellular senescence and COVID-19, including its after-effects.
*Illustrative imageGut bacteria that induce cellular senescence
The lab aims to identify gut bacteria that induce cellular senescence and to clarify their relationship with colorectal cancer.
*Illustrative imageMethods for eliminating senescent cells
The lab aims to develop methods to specifically remove senescent cells from the body.
MembersFaculty
The members of the Hara Lab consist of faculty, corporate joint researchers, project technical staff, technical assistants, project administrative staff (secretary), and graduate students.As of 2026
- ProfessorEiji Hara
- LecturerMasahiro Wakita
- Assistant ProfessorKen Uemura
- Assistant ProfessorNoriko Shinjyo
- Project Assistant ProfessorYumi Katayama
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Hara Lab
Takakura LabResearch Institute for Microbial Diseases, Department of Environmental ResponsesMolecular mechanisms of blood vessel formation and their app…
Kamimoto LabResearch Institute for Microbial Diseases, Department of Environmental ResponsesElucidating how cells and tissues are formed and maintained,…
Kotani LabResearch Institute for Microbial Diseases, Department of Environmental ResponsesBasic research toward novel therapies for intractable infect…
Yamamoto LabResearch Institute for Microbial Diseases, Department of Molecular Microbiology and ImmunologyElucidating the molecular mechanisms of host-pathogen intera…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Cellular senescence” Velichko Artem / CC BY 4.0 (cropped)
- Cellular senescence and COVID-19: “Covid-19 SP - UTI V. Nova Cachoeirinha” Gustavo Basso / CC BY-SA 4.0 (cropped)
- Gut bacteria that induce cellular senescence: “Blausen 0246 ColorectalCancer” Blausen Medical Communications, Inc. / CC BY 3.0 (cropped)
- Methods for eliminating senescent cells: “Microtubules in Primary Mouse Embryonic Fibroblasts” Howard Vindin / CC BY 4.0 (cropped)
- Related lab (情報伝達分野 高倉研究室): “Bovine Pulmonary Artery Endothelial Cells Fluorescent Image 3” Erin Rod / CC BY 4.0 (cropped)
- Related lab (システム生命医科学分野 神元研究室): “Beckman Coulter CEQ 8800” Herodotptlomeu / CC BY-SA 4.0 (cropped)
- Related lab (感染腫瘍制御分野 幸谷研究室): “Epstein-Barr Virus (EBV) Particles” NIAID / CC BY 2.0 (cropped)
- Related lab (感染病態分野 山本研究室): “T. gondii tachyzoites” Persian Microbiologist / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.