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細胞機能デザイン研究室(戸田研)
Showing the original Japanese · View translation
細胞どうしのやり取りを設計し、組織のできかたを探る研究室。

AboutAbout the lab
細胞の機能を、設計して合成する。
細胞機能
細胞どうしの
生体で
細胞間相互作用の
Key terms
- 合成生物学
- 必要な
分子や 細胞を 設計して 細胞に 実装し、 生命機能を 人工的に 作り出して 検証する 研究分野 - モルフォゲン
- 発生の
過程で 拡散して 濃度勾配を つくり、 濃度に 応じて 細胞の 分化を 空間的に 制御する 分泌因子 - synNotch
- 細胞間で
互いの 遺伝子発現を 制御できる 人工受容体。 哺乳細胞に 人工の 細胞間相互作用を つくれる - 細胞医薬
- 体内環境を
認識して 局所的に 治療因子を つくり、 病変組織で 薬と して 働く 細胞
NewsLab news
戸田准教授が、
日本生化学会の 令和8年度奨励賞を 受賞 金沢大学との
共同研究の 論文が、 Nano Letters誌に 掲載 戸田准教授が、
令和7年度 大阪大学賞を 受賞 『臨床免疫・
アレルギー科』に、 synNotchを 応用した 細胞医薬の 和文総説が 出版 『生化学』に、
モルフォゲンシグナルの 再構成に ついての 和文総説が 出版
ResearchResearch themes
細胞が
*Illustrative image細胞接着で多層構造をつくる
人工受容体
*Illustrative image人工モルフォゲンで模様を設計
生理作用の
*Illustrative image自ら育つ組織を人工的につくる
内腔や
*Illustrative image細胞医薬の開発
体内の
MembersFaculty
細胞機能
- Associate Professor戸田 聡
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Synthetic Biology Research at NASA Ames” Alexander van Dijk from San Francisco, United States / CC BY 2.0 (cropped)
- 細胞接着で
多層構造を つくる : “Epithelzellen3325” Mkaercher / CC BY-SA 3.0 (cropped) - 人工モルフォゲンで
模様を 設計: “Pattern formation 3” Jobsarayutw / CC BY-SA 4.0 (cropped) - 自ら
育つ組織を 人工的に つくる : “SEM micrograph of influenza A virions infecting primary human airway organoid cultures showing differentiated cilia” Phage1990 / CC BY 4.0 (cropped) - 細胞医薬の
開発: “Healthy Human T Cell” NIAID/NIH / Public domain (cropped) - Related lab (細胞システム研究室
(岡田研) ): “Fluorescence micrograph of Thalassiosira nanae” Terry J. McGenity, Amare Gessesse, John E. Hallsworth, Esther Garcia Cela, Carol Verheecke-Vaessen, Fengping Wang, Max Chavarría, Max M. Haggblom, Søren Molin, Antoine Danchin, Eddy J. Smid, Cédric Lood, Charles S. Cockell, Corinne Whitby, Shuang-Jiang Liu, Nancy P. Keller, Lisa Y. Stein, Seth R. Bordenstein, Rup Lal, Olga C. Nunes, Lone Gram, Brajesh K. Singh, Nicole S. Webster, Cindy Morris, Sharon Sivinski, Saskia Bindschedler, Pilar Junier, André Antunes, Bonnie K. Baxter, Paola Scavone and Kenneth Timmis Photograph by Philippe Laissue. / CC BY-SA 4.0 (cropped) - Related lab (膜システム生物学研究室
(西村研) ): “Plasma membrane structure diagram” Rosanna Hartline (RosieScienceGal) / CC BY 4.0 (cropped) - Related lab (計算生物学研究室
(水口研) ): “Linuron-3D-molecular-model-engraved-render-CAS-330-55-2” MolGod Scientific / CC BY-SA 4.0 (cropped) - Related lab (蛋白質構造データバンク構築研究室): “Neuraminidase Ribbon Diagram” NASA / Public domain (cropped)
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