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1,294 labs · 618 student voices
Daiju Kitagawa, Professor
Bio & Life Sciences1 student voices
The lab aims to understand the mechanisms of cell division, which proceeds through many stages, and to develop that understanding into drug discovery, including new anticancer drugs. It focuses in particular on centrosome duplication and on how the spindle forms and segregates chromosomes. Centering on the relationship between proteins and non-coding RNAs, the lab combines a wide range of methods, including cell biology, biochemistry, structural biology, and simulation. The lab also reproduces in vitro the interactions between cells that take place in the body, in order to clarify the molecular mechanisms behind them.
Junken Aoki, Professor
Bio & Life Sciences1 student voices
The Health Chemistry Lab studies the functions of lipids and lipid-related molecules at the cellular and whole-organism levels. Biological membranes are made up of more than 1,000 types of lipid molecules, and each one is thought to have its own specific function. Because lipids are not directly encoded by genes, studying their functions is a far more difficult challenge than studying proteins. Using technologies such as mass microscopy and mass spectrometry, the lab works to clarify the functions of a wide variety of phospholipids.
Koh Takeuchi, Professor
Bio & Life Sciences1 student voices
The Biophysical Chemistry Lab studies how the molecules that sustain life move and function. Using physical chemistry methods centered on nuclear magnetic resonance (NMR), the lab observes the dynamic behavior of molecules and seeks to clarify how those molecules contribute to the workings of the body. The lab pursues "dynamic structure-based drug discovery," which actively applies the motions of proteins and RNA to drug discovery. The lab also develops new NMR methods, such as measurements of high-molecular-weight proteins and analyses inside living cells.
Masanobu Uchiyama, Professor
Chemistry & Catalysis1 student voices
The Fundamental Organic Chemistry Lab studies the properties and phenomena of matter, seeking to understand them through the "language of chemistry": molecules, atoms, and electrons. The lab develops reactions that freely control the bonds between atoms, with the aim of creating functional materials. The lab develops techniques to precisely design and synthesize molecules as small as one billionth of a meter (a nanometer) or less. Built on three pillars (synthetic organic chemistry, spectroscopy and physical chemistry, and theoretical chemistry and computational science), the lab pursues chemistry that crosses disciplinary boundaries.
Motomu Kanai, Professor
Chemistry & Catalysis1 student voices
The lab studies synthetic organic chemistry, in which molecules are designed and made, with new catalytic reactions at its core. Research proceeds in three areas: creating molecules, creating functions, and creating order. The lab also works on drug discovery based on a new concept: having chemical catalysts act inside the body to treat disease. Aiming for substantial, long-term research that looks 10 to 20 years ahead, the lab provides a place where students can experience the excitement of cutting-edge research.
Yuko Otani, Associate Professor
Chemistry & Catalysis1 student voices
The Medicinal Chemistry Lab discovers new phenomena in organic chemistry, tests how general they are, and uses them to create functional organic molecules. Its goal is to build an integrated form of organic chemistry in which the chemical phenomena the lab has discovered are applied to the creation of biologically active molecules. The lab is interested not only in synthesizing highly active compounds but also in understanding, at the level of protein structural chemistry, how their activity arises from their structure. By exploring the new organic chemistry and new functions that novel molecular structures generate, the lab pursues new concepts that are broadly applicable.
Tetsuo Shibuya, Professor
Medicine & Healthcare1 student voices
Shibuya Lab researches and develops medical data informatics technologies to accelerate medical science research in the era of personalized genomic medicine. With advances such as next-generation sequencers, a wide variety of large-scale data is accumulating in medical science at a furious pace. The lab advances research on big data algorithms and related topics from two sides: applications to bioinformatics and the foundations of information science. The lab is located in the Human Genome Center at the Institute of Medical Science, and also uses the center's supercomputer for its research.
Emi Nishimura, Professor
Bio & Life Sciences1 student voices
The lab studies the mechanisms of regeneration, aging, and carcinogenesis, focusing on tissue stem cells, which are essential for maintaining tissues. Starting from the discovery of melanocyte stem cells, which give rise to black hair, and of their niche, the lab tests its hypotheses by confirming them through direct observation. Using skin, which can be observed in real time, as a model, the lab tracks the fate of stem cells over long periods, aiming to deepen understanding of aging in organs and in the body as a whole. The goal is to apply these findings to overcoming intractable diseases and promoting healthy longevity.
Noriko Yamamoto-Mitani, Professor
Medicine & Healthcare1 student voices
The Palliative Care Nursing lab conducts broad research on long-term nursing care for older adults and their families. Starting with the development of indicators, the lab considers how to measure and improve the quality of care in home settings and long-term care facilities. The lab treats the well-being of the nurses and care workers who provide care as inseparable from improving its quality. The lab also carries out case study research that examines individual cases one by one, building up new knowledge of care.
Takahiro Higashi, Professor
Medicine & Healthcare1 student voices
The Public Health and Health Policy Lab focuses on empirical analysis related to health care policy, health policy, and health management. In addition to disease prevention and early detection, the lab covers what is known as health services research, including access to care, systems for delivering care, and quality of care. The lab always keeps its contribution to society in mind, and places importance on focusing on what is actually happening in Japan's society, health care, and policy settings. The lab was established in 1947 as the first department of public health in Japan.
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