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11 labs · 4 student voices
Other departments in Faculty of Pharmaceutical Sciences ›Faculties at The University of Tokyo ›
Taisuke Tomita, Professor
Medicine & Healthcare1 student voices
The lab studies the pathology of neuropsychiatric diseases such as Alzheimer's disease, autism, and Parkinson's disease. Using biochemistry and molecular biology, the lab investigates what happens at the molecular and cellular levels, using both cultured cells and animal models. From this work, the lab aims to identify new drug targets and publish findings that lead to the development of therapeutics. The lab also pursues collaborative research with researchers in organic chemistry, structural biology, and clinical medicine, as well as with pharmaceutical companies.
Hiroyuki Kusuhara, Professor
Medicine & Healthcare1 student voices
The Molecular Pharmacokinetics Lab studies how drugs are absorbed, distributed, and excreted in the body. The lab investigates the factors that determine how drugs move, in particular the mechanisms by which drugs pass through cell membranes. By incorporating into mathematical models the actions of transporters, which carry substances across membranes, and of drug-metabolizing enzymes, the lab aims to predict drug efficacy and side effects from the dose. The lab also works on developing treatments for intractable pediatric liver diseases, and on research that uses computers to convert data on chemical compounds and pathology images into numerical form.
Shohei Hori, Professor
Bio & Life Sciences1 student voices
The Immunology and Microbiology Lab studies how the immune system determines "self" through its interactions with the environment. Even organisms that are genetically "non-self," such as gut bacteria, are largely judged by the immune system to be part of "self," and coexist with it rather than being eliminated. When this mechanism of immune tolerance breaks down, it leads to the onset of autoimmune diseases, inflammatory bowel disease, allergy, cancer, and infectious diseases. The lab focuses on regulatory T cells that respond to "self," aiming to elucidate the underlying principles and to apply the resulting findings to the treatment of diseases.
Toshiyuki Shimizu, Professor
Bio & Life Sciences1 student voices
The Protein Structural Biology Lab determines the three-dimensional structures of biological macromolecules such as proteins, and of their complexes, at the atomic level. Structural biology is a field that seeks to understand how molecules function and how biological phenomena arise by depicting the shapes and interactions of molecules in a visible form. Built around X-ray crystallography, the lab also incorporates small-angle X-ray scattering and single-particle analysis by cryo-electron microscopy. With applications to drug discovery in mind, the lab targets biological macromolecules that are important from medical and pharmaceutical perspectives.
Ataru Igarashi, Project Associate Professor
Medicine & Healthcare0 student voices
The Health Policy and Public Health Lab is a Social Cooperation Program of the Graduate School of Pharmaceutical Sciences, and studies health policy and public health. The lab aims to generate evidence (scientific grounds) tailored to clinical needs and to propose value-based health policy. A key challenge for the lab is to allocate healthcare resources appropriately based on evidence, so that both the public healthcare system and innovation can be sustained.
Urano Yasuteru, Professor (Concurrent)
Medicine & Healthcare0 student voices
The lab studies the evaluation of the efficacy and safety of pharmaceuticals, as well as the systems for their development and regulation. Its research and education go beyond the scientific evaluation of drugs to cover their medical and social value, as well as drug administration and legal systems. Its aims are to train the specialists needed to bring pharmaceuticals into practical use, to raise the quality of clinical trials and new drug approval reviews, and to get the drugs patients want to the clinical setting sooner. In addition to graduate students, the lab offers lectures and courses that professionals from pharmaceutical companies and government agencies can also take.
Hiroki Satoh, Associate Professor
Medicine & Healthcare0 student voices
The Drug Lifetime Management Lab studies ways to help medicines that have reached the market realize their full potential. This approach is called Drug Lifetime Management (DLM). The lab analyzes post-marketing information collected from healthcare and nursing care settings, homes, and pharmaceutical companies, aiming to apply it to the proper use of medicines and to post-marketing drug development. The lab also works on building educational systems to train the people who will carry out DLM.
Tappei Takada, Professor
Medicine & Healthcare0 student voices
The Clinical Pharmacokinetics Lab is part of the Department of Pharmacy at the University of Tokyo Hospital, and conducts research to understand the living body as a single system. The lab clarifies not only how each molecule that makes up the body functions, but also how these molecules combine to operate as a whole. Using systems pharmacology approaches, the lab aims to identify effective drug targets and to predict adverse drug reactions at an early stage. The lab also conducts clinical research on patients who visit the hospital.
Yuji Ikegaya, Professor
Bio & Life Sciences0 student voices
The Chemical Pharmacology Lab studies plasticity, the ability of the brain to be active on its own and to change itself through that activity. Brain development, memory, and diseases such as depression and dementia can all be understood as some kind of change occurring in the brain. The lab investigates how brain circuits are built, how they work, and how they break down, and explores ways to treat, prevent, and diagnose brain diseases. Through this research, the lab aims to contribute to drug discovery science.
Shohei Hori, Professor (Concurrent)
Bio & Life Sciences0 student voices
The Molecular Oncology Pharmacology Lab is a Social Cooperation Program of the Graduate School of Pharmaceutical Sciences, and studies hematopoietic stem cells and hematologic malignancies (blood cancers). In basic research, the lab aims to elucidate biological phenomena; in areas closer to clinical application, it aims to study disease mechanisms, drug resistance, and combination therapies. A distinguishing feature of the lab is that it has developed an efficient gene transfer method using retroviral vectors and uses it to advance its research. Research is conducted through open discussion.
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