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28 labs · 2 student voices
Other departments in School of Science ›Faculties at Nagoya University ›
Naoyuki Uchida, Professor
0 student voices
The Multicellular Order Research Group uses plants to study how the order of the body arises when diverse cells communicate with one another and act in coordination. The group aims to clarify how order among groups of cells is created and maintained, and how it changes depending on circumstances. The group works on identifying the signaling molecules that carry information between cells, elucidating the mechanisms of that signaling, and analyzing the functions of the related genes. The group also explores new ways of controlling multicellular order, using artificial compounds with novel activities that it discovered itself.
Yasuomi Tada, Professor
0 student voices
The Plant Molecular Signaling Group is a research group in the Plant Genome Analysis Division of the Center for Gene Research. Lecturer Mika Nomoto was selected for the Young Scientists' Award in the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology (fiscal 2024) for her research on plant immune mechanisms regulated by environmental stress. Lecturer Nomoto discovered that trichomes on the leaf surface activate immune responses when they receive mechanical stimulation such as rain.
Tsuyoshi Hirota, Project Associate Professor
0 student voices
The Time-Controlling Molecules Lab studies the circadian clock, which governs daily rhythms in many bodily functions, such as sleep-wake cycles and metabolism. It is known that disruption of the circadian clock, through shift work or genetic mutations, can lead to diseases such as sleep disorders, metabolic diseases, and cancer. Combining biochemistry and chemical biology, the lab uses original compounds to study how the circadian clock works at the molecular level. The lab is located at the Institute of Transformative Bio-Molecules (ITbM) and is introduced on the website as the "Kay-Hirota Group."
Yoshikatsu Sato, Project Associate Professor
0 student voices
The Photobiology Group studies the private life of plants through live-cell analysis built on live-imaging technology. While continuing to observe living cells, the group investigates the positioning of organelles, the elongation of pollen tubes and root hairs, the movement of plant hormones, and the mechanisms of plant regeneration. The lab has an environment where techniques from other fields can be used routinely, such as small-molecule fluorescent probes made by organic synthesis and microfluidic channels made by microfabrication. The group can also use the cutting-edge imaging equipment of the Nagoya University Live Imaging Center.
Akie Shimotohno, Project Lecturer
0 student voices
The Plant Pattern Formation Lab studies how plants sense external stimuli and use that information to build tissues. Because plants cannot move, they have developed the ability to cope with environmental stresses such as temperature fluctuations and drought. At the molecular level, the lab investigates the key factors in signal transduction in response to environmental stress, as well as the mechanisms that form and maintain the stem cells supporting the growth of roots, stems, and leaves. On the lab's website, the lab is introduced under the name "Torii Group."
Hidekazu Hiroaki, Professor
0 student voices
The Structural Molecular Pharmacology Lab conducts research in drug discovery science using the three-dimensional structures of proteins and nucleic acids. Two units work in close cooperation: a group that pursues structure-based drug discovery targeting proteins, and the Kodama Group, which pursues drug discovery using structurally controlled nucleic acids. The main method used, nuclear magnetic resonance (NMR) spectroscopy, is well suited to determining the structures of small protein domains and to rapidly detecting their interactions with low-molecular-weight drugs. On the lab's website, the lab is introduced as being able to cover everything from genome-based drug discovery to preclinical research within a single lab.
Atsunori Oshima, Professor
0 student voices
The Cellular Physiology Lab studies the three-dimensional structures and functions of membrane proteins such as channels and G protein-coupled receptors, aiming to understand how signals are transmitted across membranes. The lab performs high-resolution structural analysis by cryo-electron microscopy and develops the techniques needed for it, combining structural biology, biochemistry, cell biology, and computational science. The lab revealed the high-resolution structure of innexin-6, a gap junction protein of the nematode, and proposed a gating model in which lipids enter the channel pore and block it. The lab's website is that of the Cellular and Structural Physiology Institute (CeSPI), and its news section also lists the institute's seminars and other events.
Fumitaka Osakada, Professor
0 student voices
The Cellular Drug Efficacy Analysis Lab studies, at the level of neural circuits, how the brain processes and learns from information from the outside world. The brain predicts its surroundings using an "internal model" built from memory and experience, and it perceives the external world by correcting the error between that prediction and incoming sensory information (prediction error). Focusing on this predictive function, the lab uses tools such as virtual reality and neural organoids made from human iPS cells to elucidate the pathology of neurological and psychiatric disorders and to develop new treatments. Students in the Faculty of Science can join the lab from the second half of their third year, and lab tours are accepted at any time.
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