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16 labs · 2 student voices
Other departments in Faculty of Science ›Faculties at Chiba University ›
Akira Matsura, Professor
1 student voices
The Cell Function Regulation Lab studies the mechanisms that allow cells to proliferate and survive over time. Cell function declines with the number of cell divisions and the passage of time, a process called cellular senescence. Its causes are varied, including genome damage, dysfunction of organelles, and protein denaturation. Using budding yeast, pathogenic fungi, cultured mammalian cells, and mice, the lab investigates the molecular mechanisms from the perspectives of chromosome maintenance and protein quality control.
Masashi Murakami, Professor
1 student voices
The Functional Ecology Lab studies how the diversity of living things arises and is maintained. There are countless species on Earth, and within each species individuals also differ from one another. The lab examines how this diversity has changed over the long history of evolution and, more recently, through climate change and human activity. Working in forest, river, snow and ice, and island ecosystems and with experimental populations, the lab studies a wide range of organisms, including insects, fish, plants, and microorganisms.
Michio Ogasawara, Associate Professor
0 student voices
The Gene Function and Morphology Lab studies how the form and function of animal bodies have evolved. Its clues come from sea squirts and amphioxus, which belong to the same group as humans: the chordates. Because animals live by taking in food, the lab focuses on the organs around the digestive tract and the genes that work in them. It takes on unsolved questions, such as how the endostyle of sea squirts is connected to the thyroid gland of vertebrates.
Kiyoe Ura, Professor
0 student voices
The Chromatin Metabolism Regulation Lab studies the function of histones, the proteins that genomic DNA wraps around. Inside the cell nucleus, DNA wraps around histones to form a structure called chromatin. DNA reactions such as replication, transcription, repair, and recombination all take place on this chromatin. The lab focuses on chemical modifications of histones and investigates how they work from two sides: gene expression and DNA repair. The lab is jointly run by Professor Kiyoe Ura and Associate Professor Akira Sassa, and the two share common research rules and the same broad research direction.
Akihisa Osakabe, Associate Professor
0 student voices
The Epigenome Structure and Dynamics Lab studies the behavior of transposons, which move around within the genome. Transposons make up a large part of plant and animal genomes. While they are a driving force of evolution, they can also disrupt gene function. For this reason, many organisms tightly suppress transposons so that they are not expressed. Using the model plant Arabidopsis thaliana, the lab investigates this suppression and the mechanisms that evade it, from the molecular level to the whole organism.
Kohji Ito, Professor
0 student voices
The Biological Molecular Motor Lab studies myosin XI, a motor protein found in plants. Myosin is present in all eukaryotes and forms a large family divided into 79 classes. Plants cannot move, yet myosin XI, found only in plants, moves faster than any other class. Using biochemical and biophysical methods, the lab investigates its function and roles at levels ranging from single molecules to whole plants.
Asako Terasaki, Lecturer
0 student voices
The Neural Proteomics Lab studies lasp-2, a novel actin-binding protein discovered in the chicken brain. When neurons form networks, the growth cone at the tip of the axon keeps moving until it reaches its target. Actin-binding proteins are essential for the formation of these growth cones and of spines on the receiving side. The lab examines how lasp-2 functions and is regulated in neurons and astrocytes, and how it has evolved.
Hiroyuki Ishikawa, Associate Professor
0 student voices
The Developmental Genetics Lab studies how animal bodies are formed. The form of a multicellular organism is built and maintained according to a genetic program unique to that organism. The lab believes that even seemingly complex phenomena can be understood as combinations of events at the level of cells and molecules. Focusing on cell-to-cell communication, the lab combines in vitro biochemistry with genetics using Drosophila melanogaster.
Reiko Tajiri, Associate Professor
0 student voices
The Morphogenesis Lab studies how organisms make the materials that shape their own bodies. Like vertebrate bone and plant cell walls, the cuticle, which is the shell and skin of insects, is a matrix built outside the cell (an extracellular matrix). The properties of the cuticle are remarkably diverse: the hardness of a rhinoceros beetle, the brilliance of a jewel beetle, the water repellency of a water strider's legs. The lab studies how insects build, outside their cells, the nano- to micro-scale three-dimensional structures that give rise to these properties.
Naruki Sato, Associate Professor
0 student voices
The Muscle Developmental Biology Lab studies how muscle is built and how it works. For a muscle cell to contract, the proteins it has made must assemble correctly into myofibrils. Another question the lab wants to answer is how the assembled proteins produce coordinated contraction. Using the regulation of contraction by troponin and the function of myosin-binding proteins as clues, the lab investigates these mechanisms.
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