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Photonic Biotechnology Lab [Institute of Scientific and Industrial Research]
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A biology lab built around glowing proteins and microscopy.
AboutAbout the lab
Research on glowing proteins and microscopy.
The Photonic Biotechnology Lab conducts research on fluorescent proteins, bioluminescent proteins, and microscopy.
The lab's website says it does research that is only possible by integrating optics, engineering, physics, chemistry, cell biology, developmental biology, botany, biotechnology, and pharmaceutical sciences.
The news section lists papers on a fluorescent sensor that visualizes contact between cells and on photoswitchable fluorescent proteins.
The lab's website presents it as the "Nagai Lab" and states that it accepts graduate students from the Graduate School of Frontier Biosciences and the Graduate School of Pharmaceutical Sciences, and also recruits widely from other universities.
Key terms
- Fluorescent protein
- A protein that glows when illuminated with light. It is attached to molecules inside cells and used as a marker
- Bioluminescent protein
- A protein that works when a living organism produces light by itself. It glows without being illuminated
- Fluorescent sensor
- A molecule that makes events inside cells or between cells visible through changes in how it glows
NewsLab news
Paper on machine-learning-based denoising published in Biophysics and Physicobiology, and selected for the cover art
Paper on Gachapin, a fluorescent sensor that visualizes cell-cell contact, published in Cell Reports Methods
Review of photoswitchable fluorescent proteins published in Nanoscale
Review of Autonomous Bioluminescence Systems published in JACS Au
PhD student receives a Student Presentation Award from the Biophysical Society of Japan
ResearchResearch themes
The research page lists topics such as fluorescent proteins, bioluminescent proteins, microscopy, and green biotechnology. The website's news section includes a review of photoswitchable fluorescent proteins and a review of autonomous bioluminescence systems.
View More ↗MembersFaculty
Members of the Nagai Lab consist of faculty, postdoctoral researchers, doctoral, master's, and undergraduate students, research students, project administrative staff, and technical assistants.As of 2026
- Distinguished ProfessorTakeharu Nagai
- Associate ProfessorMitsuru Hattori
- Assistant ProfessorChieko Goto
- Assistant ProfessorTaishi Kakizuka
- Project Associate ProfessorTetsuichi Wazawa
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Confocal His2b sorbitol” Zirc / Public domain (cropped)
- Related lab (生命科学研究分野): “ETEM 101” Mike Marko / CC BY-SA 4.0 (cropped)
- Related lab (生体フォトニクス
（免疫学フロンティア研究センター） ): “AFM-Raman-TERS system” AAMonitor96 / CC BY-SA 3.0 (cropped) - Related lab (フォトニクスセンター
（フォトニクス領域） ): “POLARIS 4th Amplifier” Dr. Marco Hornung / CC BY-SA 4.0 (cropped) - Related lab (知識科学研究分野［産業科学研究所］
): “Subvocal speech recognition” Dominic Hart, NASA / Public domain (cropped)
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