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Molecular Correlation Chemistry Lab
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The lab creates materials that encapsulate molecules using cyclodextrins, which are cyclic sugars.
AboutAbout the lab
High-performance materials built through organic synthesis and intermolecular interactions
The Molecular Correlation Chemistry Lab (the Kida Lab) combines organic synthesis with intermolecular interactions to develop high-performance materials that are useful for environmental protection and medicine.
The lab studies materials and structures that take advantage of the molecule-encapsulating ability of cyclodextrins, which are cyclic sugars obtained from starch.
For example, the lab is developing an adsorbent that removes polychlorinated biphenyls (PCBs), a harmful substance mixed into insulating oil, and is working toward its practical use.
Key terms
- Cyclodextrin
- A starch-derived sugar in which glucose units form a ring. Its central cavity takes in molecules that match its shape and size.
- Inclusion (host–guest inclusion)
- The phenomenon in which a molecule matching the shape and size of the cavity of a cyclodextrin is taken into that cavity. The molecule can also be released by a stimulus.
- Polychlorinated biphenyls (PCBs)
- Toxic substances. Large amounts of insulating oil contaminated with them are stored in Japan, and the development of treatment methods is urgently needed.
- Channel-type assembly
- A mode of assembly in which cyclodextrins line up in a straight line through hydrogen bonds and form a cylindrical shape.
NewsLab news
A doctoral student received the Student Encouragement Award at the 64th Annual Meeting of the Japan Oil Chemists' Society
A master's student received the Outstanding Poster Presentation Award at the 47th Photochemistry Young Researchers' Meeting
A master's student received the Outstanding Oral Presentation Award at the 5th Young Researchers' Online Symposium of the Society of Physical Organic Chemistry, Japan
A master's student received the Poster Award at the 7th Oleomaterial Academic Exchange Meeting
ResearchResearch themes
By skillfully combining organic synthesis and intermolecular interactions, the lab develops high-performance materials that are gentle on people and the environment and useful for environmental protection and medicine. Most of its research concerns materials and structures that take advantage of the molecule-encapsulating ability of cyclodextrins, which are cyclic sugars.
*Illustrative imageA cyclic sugar that encapsulates molecules in oil
The lab found that appropriately chemically modified cyclodextrins (CDs) can form inclusion complexes with molecules even in oils and nonpolar solvents. Using them as an adsorbent, the lab has shown that trace amounts of PCBs mixed into insulating oil can be selectively removed, and is working toward practical application.
*Illustrative imageCD dimers with multiple linkers
The lab has easily synthesized dimers in which two CD molecules are joined by multiple linkers. These dimers show selective inclusion ability toward cis-type long-chain fatty acid esters over trans-type and saturated ones, which the lab believes will lead to precise molecular recognition tailored to target molecules.
Supramolecular structures of aligned CDs
From channel-type assemblies in which CDs line up in a straight line through hydrogen bonds, the lab builds nano- and microstructures of various shapes. When an aqueous solution of γ-CD is added dropwise to 2-propanol, microcubes with sides of several millimeters precipitate, and these can gel oils and organic solvents.
*Illustrative imageCDs with a modified ring skeleton
By a design that inserts a spacer into the CD ring skeleton, the lab has easily synthesized CD derivatives whose cavity shape and size can be freely controlled. The lab has also succeeded in the easy synthesis of "ring-bond-converted CDs," and has shown that they can include polyacrylic acid and other compounds that were previously considered difficult to include.
MembersFaculty
The Kida Lab consists of faculty, secretaries, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorToshiyuki Kida
- Assistant ProfessorDaisuke Aoki
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Supramolecular Assembly Lehn” M stone at English Wikipedia / CC BY-SA 3.0 (cropped)
- A cyclic sugar that encapsulates molecules in oil: “Encapsulation of DNA” Maxim Kutyrev / CC BY 4.0 (cropped)
- CD dimers with multiple linkers: “Solutions of organic substances for NMR analysis” Ryabitskii / CC BY 4.0 (cropped)
- CDs with a modified ring skeleton: “B-cyclodextrin” Materialscientist / CC BY-SA 4.0 (cropped)
- Related lab (物理有機化学領域): “Sumanene-3D-balls” Jynto (talk) / CC0 (cropped)
- Related lab (機能超
分子化学領域): “Brianite crystal structure (Alkemper-Fuess 1998) polyhedra model along c axis” Ra'ike (Wikipedia) / CC0 (cropped) - Related lab (分子設計化学領域): “Schrenk tube” Iodomethane / CC BY-SA 4.0 (cropped)
- Related lab (高分子バイオテクノロジー領域): “TOF mass spectrometer June2007” Mwillett4000 / Public domain (cropped)
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