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Atomic and Molecular Structure Lab
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A lab that uses X-rays to determine the shapes of proteins at the atomic level.
AboutAbout the lab
Understanding how proteins work from their shapes
The Atomic and Molecular Structure Lab determines the three-dimensional structures of proteins, which carry out biological functions, at atomic resolution by X-ray crystallography, and studies the relationship between the structure of protein molecules and their functions and properties from the perspective of structural biology.
The lab aims to elucidate how enzymes recognize their substrates and the mechanisms of their catalytic reactions, as well as the strategies by which proteins of microorganisms living in extreme high- or low-temperature environments adapt to those environments.
Key terms
- X-ray crystallography
- A method that shines X-rays on a crystal to determine the arrangement of atoms within a molecule
- Structural biology
- The field that studies how biomolecules work based on their three-dimensional structures
- Substrate
- The molecule that an enzyme acts on in a reaction
ResearchResearch themes
The lab determines the three-dimensional structures of proteins at atomic resolution by X-ray crystallography, and studies the relationship between structure and function and properties.
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MembersFaculty
- Assistant ProfessorTomomi Fujii
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “XBio illustration – X-ray Crystallography” explorebiology / CC BY 4.0 (cropped)
- Structures of Enzymes and Extremophile Proteins: “PDB 1hf9 EBI” Jawahar Swaminathan and MSD staff at the European Bioinformatics Institute / Public domain (cropped)
- Related lab (複合ナノ解析化学研究領域): “Transmission electron microscope (3)” Gannu03 / CC BY-SA 4.0 (cropped)
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