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Advanced Medical Instrumentation Systems Lab
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A lab that repeatedly observes living bodies with MR microscopy to track how diseases progress.
AboutAbout the lab
Seeing the whole body, alive.
Within the body, life is sustained by networks within and between many different levels of organization.
The Advanced Medical Instrumentation Systems Lab aims to clarify such life phenomena, and the progression of disease as their breakdown, by visualizing whole living individuals at high resolution with imaging technologies such as MR microscopy.
Using animal models of small fish such as medaka, the lab observes the same individual over time. Its work spans a wide range of challenges, from building disease models to developing instruments and analyzing images.
Key terms
- MR microscope
- A device that uses the principles of MRI to image the inside of small organisms in fine detail
- Disease model
- An animal or similar system created to show a condition resembling a human disease
- Imaging biomarker
- A feature extracted from images that indicates the state of a disease
ResearchResearch themes
To see the networks inside disease models, the lab focuses on developing systems that visualize whole models at high resolution.
*Illustrative imageDeveloping MR microscopy systems
The lab develops MR microscopes, which achieve high-resolution MRI so that it can be used as a microscope. It also works on image analysis that extracts features called imaging biomarkers from the captured images.
*Illustrative imageTracking disease progression in medaka
The lab uses medaka as a model of human disease, and also develops methods for handling aspects such as anesthesia during imaging, as well as methods for observing the same individual over time.
MembersFaculty
- Associate ProfessorTomohiro Ueno
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Nihonmedaka” NOZO / CC BY 3.0 (cropped)
- Developing MR microscopy systems: “Resolution vs SNR” Kosekatsumi / CC BY-SA 3.0 (cropped)
- Tracking disease progression in medaka: “Medaka (Oryzias latipes) egg, day 0” Ethmostigmus / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Research and Development Lab): “Follicular lymphoma -- low mag” Nephron / CC BY-SA 3.0 (cropped)
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