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Pharmacometrics and Systems Pharmacology Lab
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The lab predicts how drugs work using mathematical models, aiming for drug therapy tailored to each individual.
AboutAbout the lab
Toward optimal drug therapy through mathematical models.
The Pharmacometrics and Systems Pharmacology Lab conducts research in pharmacometrics, which uses mathematical models and simulation to quantitatively analyze and predict drug responses (movement in the body, effects, and side effects), and in systems pharmacology, which views the body and disease as a single system to elucidate the interactions among drugs, the body, and disease.
The lab aims to predict disease progression and the effects and side effects of drugs at both the population and individual levels, and to apply these predictions to optimal drug therapy in practice and to drug development.
The lab conducts research and education in collaboration with its other research base, a lab at Cincinnati Children's Hospital in the United States.
Key terms
- Pharmacometrics
- A research field that uses mathematical models and simulation to quantitatively predict the movement, effects, and side effects of drugs
- Precision dosing
- Using mathematical models or AI to determine the drug dose best suited to each individual patient
- Virtual clinical trial
- Simulating a clinical trial on a computer and using the results for purposes such as trial planning
ResearchResearch themes
Through research, development, and implementation in society of pharmacometrics and systems pharmacology, the lab aims to promote personalized drug therapy in practice and fast, efficient, and safe drug development.
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MembersFaculty
- Visiting ProfessorTomoyuki Mizuno
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Infusion pump 2” Senior Airman Andrea Posey/U.S. Air Force / Public domain (cropped)
- Drug therapy and drug development using mathematical models: “Infusionspumpe” Pflegewiki-User Würfel / CC BY-SA 3.0 (cropped)
- Related lab (数理生命医学): “Mast Cell (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
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