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RIKEN Neural Stem Cell Research Lab
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The lab investigates neural stem cells and the developmental clock at the level of genes.

AboutAbout the lab
Tackling the mysteries of development through transcription factors.
The RIKEN Neural Stem Cell Research Lab studies mammalian development at the level of transcription factors, with a focus on the development of the nervous system.
The lab takes on the question of how, as a single fertilized egg becomes a complex organism, cells recognize their position and role and carry out specific events at specific times.
The lab is a collaborative program with the RIKEN Neural Stem Cell Research Team, and it is located at RIKEN in Kobe.
Key terms
- Neural stem cell
- A stem cell that proliferates and produces neurons and glial cells
- bHLH factor
- A group of transcription factors that regulate gene activity
- Segmentation clock
- A gene-based clock that produces somites, the precursors of the vertebral column in the embryo, at regular intervals
ResearchResearch themes
In neural development, the proliferation of neural stem cells, the differentiation of neurons, and the differentiation of glial cells occur in sequence. The lab has shown that every one of these steps is controlled by bHLH factors.
View More ↗MembersFaculty
- Visiting ProfessorRyoichiro Kageyama
- Program-Specific Assistant ProfessorTomoko Tateya
- Program-Specific Assistant ProfessorHiromi Shimojo
- Associate ProfessorToshiyuki Ohtsuka
- Assistant ProfessorTaeko Kobayashi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Neural stem cell” Joseph Elsbernd / CC BY-SA 2.0 (cropped)
- Neural stem cells and the developmental clock: “Neural Stem Cells” Welcome Collection / CC BY-SA 4.0 (cropped)
- Related lab (Pulmonary Morphogenesis Lab): “3D Medical Animation Bronchus Description” https://www.scientificanimations.com / CC BY-SA 4.0 (cropped)
- Related lab (Gastrointestinal Tumor Control and Organ Regeneration Surgery Lab): “Plastic Surgeon Performing Surgery in Operating Room” Tyler Frew MD / CC BY-SA 4.0 (cropped)
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- Related lab (Clinical Statistics Lab): “Box Plot Picture” The Twists and Turns / CC0 (cropped)
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