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Radiation Oncology and Image-Applied Therapeutics Lab
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A lab that explores, through biology and physics, technologies to treat cancer with radiation more precisely and more powerfully.
AboutAbout the lab
Advancing radiotherapy through biology and physics
The Radiation Oncology and Image-Applied Therapeutics lab aims to develop innovative radiotherapy technologies for malignant tumors and other conditions, and to apply them in the clinic to improve treatment outcomes.
In molecular biology research, the lab investigates why some tumors respond poorly to radiotherapy and develops ways to overcome this resistance.
In physics and engineering research, the lab develops high-precision radiotherapy technologies, such as intensity-modulated radiation therapy and four-dimensional radiotherapy, which accounts for motion inside the body.
The lab welcomes physicians, biologists, and physicists and engineers who are interested in clinical cancer care and in research and development.
Key terms
- Intensity-modulated radiation therapy
- Treatment that finely varies the intensity of the radiation as it is delivered, concentrating it on the cancer and reducing the effect on surrounding organs (IMRT)
- Neutrophil extracellular traps
- Web-like structures that neutrophils release outside the cell. They can be involved in cancer metastasis
- Boron neutron capture therapy
- Treatment in which neutrons are directed at boron that has accumulated in the cancer, destroying only the cancer cells (BNCT)
ResearchResearch themes
The lab conducts research to make radiotherapy more effective and safer from three angles: biology, physics, and clinical practice.
*Illustrative imageBiological research on radiotherapy
The lab carries out a broad range of basic cancer research, including developing drugs that enhance the effects of radiotherapy and studying neutrophil extracellular traps, which cause distant metastasis. It also collaborates with research institutes within the university on topics such as boron neutron capture therapy.
*Illustrative imagePhysical research on concentrating radiation
The lab has co-developed a high-precision image-guided radiotherapy system with a Japanese company and evaluates it in the clinic.
*Illustrative imageClinical research on new radiotherapy
The lab brings findings from its biology and physics research, along with new treatment technologies, into the clinic. It actively conducts clinical studies such as multidisciplinary treatment that combines high-precision radiotherapy with surgery and chemotherapy.
MembersFaculty
- ProfessorTakashi Mizowaki
- Associate ProfessorMichio Yoshimura
- LecturerYusuke Iizuka
- LecturerMegumi Uto
- Assistant ProfessorRyota Nakashima
- Assistant ProfessorYuka Ono
- Assistant ProfessorRihito Aizawa
- Assistant ProfessorTatsuya Suwa
- Program-Specific Assistant ProfessorNoriko Kishi
- Program-Specific Assistant ProfessorShinya Hiraoka
- Program-Specific Assistant ProfessorTakahiro Iwai
- Program-Specific Assistant ProfessorHideaki Hirashima
- Program-Specific Assistant ProfessorTakanori Adachi
- Program-Specific Assistant ProfessorYukako Kishigami
- Program-Specific Hospital Assistant ProfessorHiroyuki Inoo
- Program-Specific Hospital Assistant ProfessorTakashi Ogata
- Program-Specific Hospital Assistant ProfessorRyo Narukami
VoicesStudent voices
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Report an errorAbout the images
For images provided to us or used with permission, the source is listed on each line. Wikimedia Commons images are illustrative and were not taken at the lab (they are cropped). Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Radiation Therapy Irradiation Device” 京都大学 放射線腫瘍学・画像応用治療学 / 研究室からの
提供 (cropped) - Biological research on radiotherapy: “Neutrophil Extracellular Trap” CHDENK / CC BY-SA 4.0 (cropped)
- Physical research on concentrating radiation: “Aerial view of a model of a linear accelerator” CuriosityScribe / CC BY-SA 4.0 (cropped)
- Clinical research on new radiotherapy: “External beam radiotherapy retinoblastoma nci-vol-1924-300” Unknown photographer/artist / Public domain (cropped)
- Related lab (Medical Chemistry Lab): “Macrophage by NIAID” NIAID / CC BY 2.0 (cropped)
- Related lab (Clinical Laboratory Medicine Lab): “Body fluid cell count testing on automated analyzer” SpicyMilkBoy / CC BY-SA 4.0 (cropped)
- Related lab (Gynecology and Obstetrics Lab): “Obstetric ultrasound scan monitor showing 20-week human fetus profile in Navi Mumbai 2015” Goleisureintl / CC BY 4.0 (cropped)
- Related lab (Tumor Biology (Pathology II) Lab): “Whole slide image of H&E stained breast tumour tissue” KajsaMollersen / CC BY-SA 4.0 (cropped)
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