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Kyoto University Institute for Human Behavior and Evolution – Akari Lab
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A lab that explores the evolution and adaptation of primates through genomes and cells.

AboutAbout the lab
Uncovering the characteristics of primates through genomes and cells.
The Genome Cytology Division (Institute for Human Behavior and Evolution) studies the evolution, behavioral traits, environmental responses, and reproduction of primates, including humans, through both experiments and theory.
Its research spans levels from DNA, RNA, and proteins to cells, tissues, individuals, and the field.
The division also welcomes new research plans proposed by students.
Key terms
- GPCR
- A family of receptors located in the cell membrane that receive signals from outside the cell and pass them inside. Some of them detect taste and smell.
- Transposable element
- A DNA sequence that can move around within the genome and change its position.
- Coevolution
- The process in which interacting organisms, such as a parasite and its host, evolve while influencing each other.
ResearchResearch themes
The division studies the evolution, behavioral traits, environmental responses, and reproduction of primates (including humans) through both experiments and theory, with the goal of comprehensively elucidating the characteristics of primates.
*Illustrative imageSensory Receptors and Adaptation to the Environment
Based on genomic diversity among humans, chimpanzees, macaques, colobus monkeys, marmosets, and others, the lab studies GPCR-mediated sensory information (taste, smell, vision, etc.) and adaptation to the environment.
*Illustrative imageStem Cells, Development, and Differentiation
The lab cultures stem cells such as iPS cells, as well as neural and germ cells, to study the mechanisms of development, differentiation, and epigenetic regulation.
*Illustrative imageLarge-Scale Changes in Genome Structure
The lab studies large-scale changes in genome structure caused by repetitive sequences and transposable elements.
*Illustrative imageCoevolution of Pathogens and Hosts
The lab studies the molecular mechanisms involved in the coevolution of pathogens, such as parasites and viruses, and their hosts.
MembersFaculty
- ProfessorHirofumi Akari
- ProfessorHiroo Imai
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Macaca fuscata yakui summer 2017.jpg 05” Motohiro Sunouchi / CC BY 2.0 (cropped)
- Sensory Receptors and Adaptation to the Environment: “Rrods and cones of the primate retina” Helga Kolb / CC BY-SA 4.0 (cropped)
- Stem Cells, Development, and Differentiation: “Rhesus Macaque Mother with Infant at Asola Bhatti Wildlife Sanctuary” Gannu03 / CC BY-SA 4.0 (cropped)
- Large-Scale Changes in Genome Structure: “Bornean, Sumatran & Tapanuli orangs (horizontal)” Eric KilbyAiwokTim Laman / CC BY-SA 3.0 (cropped)
- Coevolution of Pathogens and Hosts: “Electron microscopic image of a mimivirus - journal.ppat.1000087.g007 crop” Ghigo E, Kartenbeck J, Lien P, Pelkmans L, Capo C, Mege JL, Raoult D. / CC BY 2.5 (cropped)
- Related lab (Nakano Lab, Center for Ecological Research, Kyoto University): “Otsu Omi-jingu View to Lake Biwa 1” Zairon / CC BY 4.0 (cropped)
- Related lab (Response Gene Science Lab): “DNA Repair Mechanisms” Eunice Laurent / CC BY-SA 4.0 (cropped)
- Related lab (Tochio Lab (Structural Physiology Subdivision, Department of Biophysics, Graduate School of Science, Kyoto University)): “Protein HMOX2 PDB 2q32” Emw / CC BY-SA 3.0 (cropped)
- Related lab (Plant Systematics and Taxonomy Lab): “Ranunculus lingua herbarium specimen by Joseph Witry” Musée national d'histoire naturelle Luxembourg / CC BY 4.0 (cropped)
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