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Tochio Lab (Structural Physiology Subdivision, Department of Biophysics, Graduate School of Science, Kyoto University)
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A lab that uses NMR to explore the shapes of biomolecules responsible for cellular information processing.
AboutAbout the lab
How do cells read information from the outside?
The Structural Physiology Lab (Tochio Lab) aims to elucidate the basic principles of cellular "information processing": how cells receive and respond to external stimuli.
Biomolecules such as proteins carry and process this information.
Using nuclear magnetic resonance (NMR) as the main method, together with X-ray crystallography and cryo-electron microscopy, the lab studies proteins involved in the intracellular information processing behind immune and nervous system responses, and in the regulation of genetic code translation.
Key terms
- Nuclear magnetic resonance (NMR)
- A method that uses atomic nuclei as tiny magnets to study the shapes and movements of proteins and other molecules.
- Cryo-electron microscopy
- A method in which a sample is rapidly frozen and observed under an electron microscope to determine the shapes of proteins and other molecules.
ResearchResearch themes
The lab aims to clarify, from the structure and function of biomolecules, the basic principles of cellular information processing: how cells receive and respond to stimuli from the outside world.
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MembersFaculty
The members of the Structural Physiology Lab are faculty, doctoral and master's students, fourth-year undergraduates in the Faculty of Science, and technical assistants.As of 2026
- ProfessorHidehito Tochio
- Program-Specific Associate ProfessorDaichi Morimoto
- Assistant ProfessorKayo Imamura
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Protein HMOX2 PDB 2q32” Emw / CC BY-SA 3.0 (cropped)
- Molecules Responsible for Cellular Information Processing: “Ubiquitin cartoon-2” Rogerdodd / CC BY-SA 3.0 (cropped)
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- Related lab (Quantum Chemistry Lab): “Amniote rhodopsin 3D structures” Constanze Bickelmann / CC BY-SA 3.0 (cropped)
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