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Response Gene Science Lab
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The lab investigates, at the level of genes, the mechanisms that protect living organisms from oxidative stress.
AboutAbout the lab
Molecular mechanisms for living under stress.
The Environmental Response Gene Science Division studies how living organisms respond to various environmental stresses, with a particular focus on oxidative stress.
The lab identifies genes and enzymes that respond to oxidative stress and investigates the mechanisms that repair DNA damage caused by stress.
It also examines, at the tissue and whole-organism levels, how the loss or overproduction of DNA repair enzymes affects development, aging, and lifespan.
Key terms
- Oxidative stress
- A state in which reactive oxygen species and similar molecules increase excessively and damage a cell's DNA and proteins
- DNA repair
- The mechanisms by which a cell repairs damaged DNA by itself
- Cell death
- The process by which a cell kills itself through a defined mechanism
ResearchResearch themes
The lab studies the mechanisms by which organisms respond to various environmental stresses, with a particular focus on mechanisms that deal with oxidative stress.
*Illustrative imageOxidative Stress and DNA Repair
Organisms respond to stress through the expression of genes for defense and damage repair, the induction of cell death, and other processes. The lab identifies genes and enzymes that respond to oxidative stress and investigates the mechanisms that repair DNA damage caused by stress.
*Illustrative imageDNA Repair, Aging, and Lifespan
To clarify how the loss or overproduction of enzymes that repair DNA damage affects development, aging, and lifespan, the lab also conducts research at the tissue and whole-organism levels.
MembersFaculty
The members of the Environmental Response Gene Science Division consist of faculty members, doctoral and master's students, undergraduate students, and secretaries.As of 2025
- Associate Professor秋山 秋梅
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “DNA Repair Mechanisms” Eunice Laurent / CC BY-SA 4.0 (cropped)
- Oxidative Stress and DNA Repair: “Dna-repair-12-638” Elmir Ayvazov 1999 / CC BY-SA 4.0 (cropped)
- DNA Repair, Aging, and Lifespan: “Nematode (Caenorhabditis elegans)” Database Center for Life Science (DBCLS) / CC BY 3.0 (cropped)
- Related lab (Kyoto University Institute for Human Behavior and Evolution – Akari Lab): “Macaca fuscata yakui summer 2017.jpg 05” Motohiro Sunouchi / CC BY 2.0 (cropped)
- Related lab (Theoretical Biophysics Lab): “Schematic of a single-tethered DNA curtain” Soyeong An, Youngseo Kim, and Ja Yil Lee / CC BY 4.0 (cropped)
- Related lab (Plant Molecular Physiology Lab): “Stomata of Tradescantia spathacea leaves” Trương Minh Khải / CC BY 4.0 (cropped)
- Related lab (Kyoto University Wildlife Research Center Lab): “Ailuropoda melanoleuca (Panda géant) - 445” Another one of my pictures: This photograph was taken by Medium69 (William Crochot) and released under the license stated below. You are free to use it for any purpose as long as you credit the author (William Crochot), the Source (Wikimedia Commons) and the license (CC-BY-SA 4.0) in close relation to the image. Please do not upload an updated image here without consultation with the Author. The author would like to make corrections only at his own source RAW. This ensures that the changes are preserved.Please if you think that any changes should be required, please inform the author.Otherwise you can upload a new image with a new name. Please use one of the templates derivative or extract. / CC BY-SA 4.0 (cropped)
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